We are creating the world's most trusted encyclopedia and knowledge base.
Once you join us and log in, you'll be able to edit this page instantly!

Cyclic AMP

From Citizendium, the Citizens' Compendium

Jump to: navigation, search


Image:Statusbar3.png
Main Article
Talk
Related Articles  [?]
Bibliography  [?]
External Links  [?]
 
This is a draft article, under development. These unapproved articles are subject to a disclaimer.

In biochemistry, cyclic AMP is an "adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH."[1]

Metabolism

Cyclic AMP, along with pyrophasphate, are formed by action of the enzyme adenylate cyclase on adenosine triphosphate (ATP).

Pharmacology

The medication adenosine inhibits the effects intracellular cyclic AMP thus reducing sympathetic stimulation.[2]

References

  1. ↑ Anonymous, (2008) Cyclic AMP (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Keith Parker; Laurence Brunton; Goodman, Louis Sanford; Lazo, John S.; Gilman, Alfred (2006). “Chapter 34. Antiarrhythmic Drugs”, Goodman & Gilman's the pharmacological basis of therapeutics, 11th. New York: McGraw-Hill. ISBN 0-07-142280-3. 
Retrieved from "http://reid.citizendium.org/wiki/Cyclic_AMP"
Views
Personal tools