Ancrod

From Citizendium
Revision as of 09:34, 18 January 2010 by imported>Robert Badgett (New page: In medicine, '''ancrod''' is "an enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a...)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

In medicine, ancrod is "an enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy.[1]

Ancrod has been unsuccessfully used for acute stroke.[2]

References

  1. ↑ Anonymous (2024), Ancrod (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Levy DE, del Zoppo GJ, Demaerschalk BM, Demchuk AM, Diener HC, Howard G et al. (2009). "Ancrod in acute ischemic stroke: results of 500 subjects beginning treatment within 6 hours of stroke onset in the ancrod stroke program.". Stroke 40 (12): 3796-803. DOI:10.1161/STROKEAHA.109.565119. PMID 19875736. Research Blogging.
Retrieved from "https://citizendium.org/wiki/index.php?title=Ancrod&oldid=718526"