Case-control studies/Definition

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Case-control studies [r]: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

This definition is at least in part based on: Anonymous (2025), Case-control studies (English). Medical Subject Headings. U.S. National Library of Medicine.