Antineutrophil cytoplasmic antibodies

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Revision as of 10:29, 3 October 2008 by imported>Robert Badgett (New page: {{subpages}} In medicine and rheumatology, '''antineutrophil cytoplasmic antibodies''' ('''ANCA''') are "Autoantibodies directed against cytoplasmic constituents o...)
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In medicine and rheumatology, antineutrophil cytoplasmic antibodies (ANCA) are "Autoantibodies directed against cytoplasmic constituents of polymorphonuclear leukocytes and/or monocytes. They are used as specific markers for Wegener Granulomatosis and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA."[1]

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