Amprenavir

amprenavir
IUPAC name: see chemistry section Synonyms: AMP, AMV, APV, VX-478 Formula: C25H35N3O6S
Uses:	HIV
Properties:	protease inhibitor
Hazards:	see drug interactions
Mass (g/mol): CAS #: 505.6269 161814-49-9

Amprenavir, also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- hydroxy-1-phenylbutan-2-yl]carbamate.

Brand Names

• Agenerase®
• Prozei®
• Vertex®

External Links

• The most up-to-date information about Amprenavir and other drugs can be found at the following sites.
• Amprenavir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Amprenavir - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Amprenavir - Detailed information from DrugBank.