Flavivirus

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Revision as of 11:37, 17 October 2007 by imported>David E. Volk (add kumlinge, need to expand some abbreviations yet.)
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Flavivirus genus
Virus classification
Group: Group IV ((+)ssRNA)
Family: Flaviviridae
Genus: Flavivirus
Vectors
  • Mosquito-borne
  • Tick-borne
  • No Known Vector

Flavivirus is a genus of the family Flaviviridae, named after the Yellow fever virus (Flavi = yellow). Each year, this complex of viruses causes hundreds of millions of infections, with symptoms ranging from assymptomatic, to fever and rash, neurological damage, encephalitis, hemorrhaging, shock and death. Of the flaviviruses, the four Dengue fever viruses cause the most disease each year. Both epidemic and sylavatic (jungle) strains have been found for many flaviviruses. Flaviviruses are arboviruses and are transmitted by ticks, mosquitoes, and no-see-ums (their vectors). Birds serve as a large reservoir for many viruses, but mammals, including humans and horses, are mostly dead-end hosts.

The flavivirus genus includes (see table below) the mosquito borne West Nile virus(WNV), Yellow fever virus(YFV), St. Louis encephalitis virus (SLE) and the virus that causes Dengue fever(DENV). Flavivirus also includes (Central European)-Tick-borne Encephalitis Virus, Russian-spring summer encephalitis(RSSE) and several other viruses which cause encephalitis. Some flavivirus cause sever hemorrhagic fevers, including Dengue and Omsk hemorrhagic fever virus

Flavivirus share a common size (40-60 microinches), symmetry (enveloped, icosahedral nucleocapsid), nucleic acid (positive-sense, single stranded RNA approximately 10,000-11,000 bases), and appearance in the electron microscope.

List of Flaviviruses

VirusAntigenic ComplexVector
Yellow fever virusYellow Fevermosquito
West Nile virusJapanese Encephalitismosquito
KunjinJapanese Encephalitismosquito
St. Louis EnchephalitisJapanese Encephalitismosquito
SEPIKYellow Fevermosquito
SABVYellow Fevermosquito
JUGVYellow Fevermosquito
EHVYellow Fevermosquito
Japanese EncephalitisJapanese Encephalitismosquito
Murray Valley EncephalitisJapanese Encephalitis mosquito
USUTUJapanese Encephalitismosquito
Dengue-1 virusDenguemosquito
Dengue-2 virusDenguemosquito
Dengue-3 virusDenguemosquito
Dengue-4 virusDenguemosquito
KedougaDenguemosquito
BUSSAROAmosquito
IGUAPAROAmosquito
ILHEUNTAYAmosquito
RocioNTAYAmosquito
ZikaSPONDmosquito
KokoberaKokoberamosquito
Entebbe Bat virusEntebbe BatNo Known Vector
YokoseEntebbe BatNo Known Vector
Rio Bravo virusRio BravoNo Known Vector
MMLVRio BravoNo Known Vector
Modoc virusModocNo Known Vector
ApoiModocNo Known Vector
Tick-borne encephalitisMammalian tick-borneTick
PowassanMammalian tick-borneTick
Omsk hemorrhagic feverMammalian tick-borneTick
LangatMammalian tick-borneTick
Louping-ill virusMammalian tick-borneTick
AlkhurmaMammalian tick-borneTick
Kyasanur Forest diseaseMammalian tick-borneTick
Russian-spring summer encephalitis Mammalian tick-borneTick
KARSHMammalian tick-borneTick
KumlingeMammalian tick-borneTick
MeabanSeabird tick-borneTick