Oxycodone

oxycodone
IUPAC name: (1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one Synonyms: many, see below Formula: C18H21NO4
Uses:	analgesic, narcotic
Properties:	opiod antagonist,
Hazards:	see side effects & drug interactions
Mass (g/mol): CAS #: 315.3636 76-42-6

Oxycodone is an opioid analgesic similar to codeine that is marketed with and without additional analgesics, generally NSAIDS, such as aceteminophen and aspirin.

Oxycodone has been the target of robberies of pharmacies. After robberies, oxycodone is resold in various ways including through an ice cream truck.

Mechanism of action

Oxycodone is a weak agonist of the mu, kappa and delta opiod receptors of the central nervous system. Oxycodone and other opioids inhibit the release of vasopressin, somatostatin, insulin, and glucagon. Opioids close N-type voltage-operated calcium channels (kappa-receptor agonist) and open calcium-dependent inwardly rectifying potassium channels (mu and delta receptor agonist). This results in hyperpolarization and reduced neuronal excitability.