Evolution of appetite regulating systems

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Evolution of Appetite Regulating Systems – Outline

Introduction

POMC  What it is  Where its found  what it forms  structure *diagram*

Physiology and relation to appetite regulation  Evidence for POMC related to food regulating systems  Relationship between POMC and other hormones eg leptin *diagram*

Species Variation in POMC Gene  *evolutionary tree diagram*  Chordata (vertebrates) o Agnatha – Lamprey o Gnathostomes  Chondrichthyes (cartilaginous fish)  Class Osteichthyes (bony fish) • Subclass Actinopterygii (ray-finned fish;) - paddlefish • Subclass Sarcopterygii (lobe-finned fish) o Tetrapods (mammals, birds, reptiles?)  Invertebrates

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