Ancrod
Jump to navigation
Jump to search
In medicine, ancrod is "an enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy.[1]
Ancrod has been unsuccessfully used for acute stroke.[2]
References
- ↑ Anonymous (2024), Ancrod (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Levy DE, del Zoppo GJ, Demaerschalk BM, Demchuk AM, Diener HC, Howard G et al. (2009). "Ancrod in acute ischemic stroke: results of 500 subjects beginning treatment within 6 hours of stroke onset in the ancrod stroke program.". Stroke 40 (12): 3796-803. DOI:10.1161/STROKEAHA.109.565119. PMID 19875736. Research Blogging.