CD4 antigen: Difference between revisions
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imported>Robert Badgett (New page: In medicine, the '''CD4 antigens''' are "55-kda antigens found on helper-inducer T-lymphocytes and on a variety of other immune cell types. CD4 antigens are members of the immunog...) |
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In [[medicine]], the '''CD4 antigens''' are "55-kda antigens found on [[helper-inducer T-lymphocyte]]s and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in [[major histocompatibility complex]] class II-restricted immune responses. On [[T-lymphocyte]]s they define the helper/inducer subset. CD4 antigens also serve as [[interleukin-15]] receptors and bind to the [[HIV]] receptors, binding directly to the [[HIV envelope protein G120]]."<ref>{{MeSH}}</ref> | In [[medicine]], the '''CD4 antigens''' are "55-kda antigens found on [[helper-inducer T-lymphocyte]]s and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in [[major histocompatibility complex]] class II-restricted immune responses. On [[T-lymphocyte]]s they define the helper/inducer subset. CD4 antigens also serve as [[interleukin-15]] receptors and bind to the [[HIV]] receptors, binding directly to the [[HIV envelope protein G120]]."<ref>{{MeSH}}</ref> | ||
Latest revision as of 16:25, 22 August 2010
In medicine, the CD4 antigens are "55-kda antigens found on helper-inducer T-lymphocytes and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in major histocompatibility complex class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as interleukin-15 receptors and bind to the HIV receptors, binding directly to the HIV envelope protein G120."[1]
The number of CD4-positive T-lymphocytes is called the CD4 lymphocyte count and it is reduced in Human Immunodeficiency Virus Type 1 and AIDS.
References
- ↑ Anonymous (2024), CD4 antigen (English). Medical Subject Headings. U.S. National Library of Medicine.