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==Studies/Trials:-==
==Studies/Trials:-==
<p><b>STUDIES OF THE ACTIVITY OF HOMEOPATHIC MEDICINES</b></p>
<p><b>STUDIES OF THE ACTIVITY OF HOMEOPATHIC MEDICINES</b></p>

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Studies/Trials:-

STUDIES OF THE ACTIVITY OF HOMEOPATHIC MEDICINES

ORIGINAL/TRANSLATED TITLE

AUTHOR(S)

PUBLICATION

ACTIVITY

STUDY

Inhibition of lymphoblast
transformation test (LTT) in
phytohaemagglutinin (PHA) with
Phytolacca americana in
homeopathic dilution

Colas H.,
Aubin M.,
Picard P.,
Lebecq J.C.

Ann. Homéopat.<o:p> </o:p>

Fr., 1975, 6: 1-11.

Inhibitory

Lymphoblast<o:p> </o:p>

transformation

Inquiry into the limits of biological effects of chemical compounds in tissue culture. I. Low dose effects of mercuric chloride

Mansvelt J.D.,
van Amons E.

Z. Naturtorschung,<o:p> </o:p>
1975, 30:
643-649.

Inhibitory

Lymphocyte<o:p> </o:p>

growth

The effects of Belladonna and Ferrum phosphoricum on the chemoluminescence of human poly-morphonuclear neutrophils

Poitevin B.,
     Aubin M.,
Royer J.F.

Ann. Homéop. Fr.,<o:p> </o:p>

1983, 3: 5-12.

Inhibitory

Radical release

Effect of aconitum and veratrum on the isolated perfused heart of the common eel (Anguilla anguilla)

Pennec J.P.,
Aubin M.

Comp. Biochem.<o:p> </o:p>
Physiol.
, 1984,
776: 367-369.

Protective

Aconitine toxicity

Elements of homeopathic pharmacology

Aubin M.

Homéopathie Franç., 1984, 72:231- 235

Protective

Aconitine toxicity

The effect of homeopathic preparations on the phagocyte activity of granulocytes. In vitro tests and double-blind controlled trials

Wagner H.,
     Jurcic K.,
Doenicke A.,
Rosenhuber E.,
Behrens N.

Arzneim.
Forsch./Drug Res.,
1986, 36:
1424-1425.

Stimulant

Phagocytosis

Approach to quantitative analysis of the effect of Apis mellifica on the degranulation of human basophils cultivated in vitro

Poitevin B.,
     Aubin M.,
Benveniste J.

Innov. Tech. Biol.
Med.
, 1986, 7:
64-68.

Inhibitory

Basophil<o:p> </o:p>

degranulation

In vitro stimulation of human granulocytes and lymphocytes by pico- and femtogram quantities of cytostatic agents

Wagner H.,
     Kreher B.,
Jurcic K.

Arzneim. Forsch./Drug Res., 1988, 38: 273-275.

Stimulant

Lymphocyte<o:p> </o:p>

growth

Human basophil degranulation triggered by very dilute antiserum against IgE

Davenas E., Beauvais F., Amara J., Robinson M., Miadonna A., Tedeschi A., Pomeranz B., Fortner P., Belon P., Sainte-Laudy J., Poitevin B., Benveniste J.

Nature, 1988,<o:p> </o:p>

333: 816-818.

Stimulant

Basophils

In vitro immunological degranulation of human basophils is modulated by lung histamine and Apis mellifica

Poitevin B.,
     Davenas E.,
Benveniste J.

Brit. J. Clin.
Pharmacol.
, 1988,
25: 439-444.

Inhibitory

Basophil
degranulation

Cytotoxic agents as immunomodulators

Wagner H.,
Kreher B.

Proc. of the 3rd
GIRI meetin
g,
Paris,
1989, 31-
46.

Stimulant

Lymphocyte<o:p> </o:p>

growth

Contributions of fundamental research in homeopathy

Boiron J.,
Belon P.

Berl. J. Res. Hom.,
1990, 1: 34-35.

Inhibitory

Basophil
degranulation

Synergism of action between indoleacetic acid (IAA) and highlydiluted solutions of CaCO3 on the growth of oat coleoptiles

Bornoroni C.

Berl. J. Res. Hom.,
1991
, 1 (4/5): 275-278.

Stimulant

Growth of plant cells

Study of the action of Hahnemannian dilutions of mercury chloride on the mitotic index in animal cell cultures.

Boiron J.,
     Abecassis J.,
Cotte J.,
Bernard A.M.

Ann. Homéop.Fr., 1991, 23:<o:p> </o:p>

43-49.

Protective

Hg toxicity

Dual effects of formylpeptides on the adhesion of endotoxin-primed human neutrophils

Bellavite P.,
     Chirumbolo S.,
Lippi G.,
Andrioli G.,
Bonazzi L.,
Ferro I.

Cell. Biochem.
Funct.
, 1993, 11: 231-239.

Inhibitory

Cell adhesion
(bact. pept.
10-8-10-9)

Effects of homeopathic preparations of organic acids and of minerals on the oxidative metabolism of human neutrophils

Chirumbolo S.,
     Signorini A.,
Bianchi I.,
Lippi G.,
Bellavite P.

Br. Hom. J., 1993,<o:p> </o:p>

82: 227-244.

Inhibitory

Leucocyte
     activation
(metabolism)

Platelets/endothelial cells interactions in presence of acetylsalicylic acid at ultra low dose

Doutremepuich
     C.,
Lalanne M.C.,
Ramboer I.,
Sertillanges
M.N.,
De Seze O.

Omeomed 92 (C.
Bornoroni, ed.),

1993
, Editrice
Compositori,
Bologna:
109-115.

Inhibitory

Prostacyclin<o:p> </o:p>

release

Effect of high dilutions of epidermal growth factor (EGF) on in vitro proliferation of keratinocyte and fibroblast cell lines

Fougeray S.,
     Moubry K.,
Vallot N.,
Bastide M.

Br. Hom. J., 1993,<o:p> </o:p>

82: 124-125.

Inhibitory

Growth of<o:p> </o:p>

keratinocytes

Effects of different homeopathic potencies of Lachesis on lymphocyte cultures obtained from rabbit blood

Enbergs H.,
Arndt G.

Biol. Tier., 1993, 4.

Stimulant

Mitotic and
     immunostimulating
activity (bact. pept
10-5-10-6)

The effect of homeopathic potencies of housedust mite on the migration of house-dust sensitive human leukocytes

Gibson S.L.,
Gibson R.G.

Complement.
Ther. Med.
, 1996,
4: 169-171.

Stimulant

Leucocyte
chemotaxis

The effects of Nux vomica Homaccord and Atropinum comp. on intestinal activity in vitro

Kanui T.I.,
Enbergs H.

Biol. Tier., 1996/1, 43-47.

Stimulant

Contraction of
intestinal muscles

Application of flow cytometry to the analysis of the immunosuppressive effect of histamine dilutions on human basophil action: effect ofcimetidine

Sainte-Laudy J.,
Belon P.

Inflamm. Res.,
1997, 46:
S27-S28.

Inhibitory

Basophil
degranulation

Effects of Podophillum pellatum compounds in various preparations and dilutions on human neutrophil functions in vitro

Chirumbolo S.,
     Conforti A.,
Lussignoli S.,
Metelmann H.
et Al.

Br. Hom. J., 1997;<o:p> </o:p>

86-16.

Inhibitory

Release of<o:p> </o:p>

superoxides

In vivo and in vitro studies on the efficiency of potentized and nonpotentized substances

Harisch G.,
Dittmann J.

BT, 1997, 2;<o:p> </o:p>

40-46.

Difference between potentised and non-potentised substances

In vivo and in vitro study; basic research

Experiments with the effects of Ubichinon-Injeel and strong Ubichinon-Injeel on an acellular system

Harisch G.,
Dittmann J.

BM, 1997, 3;<o:p> </o:p>

99-104.

Different effects of associations of various potencies and individual potencies

In vitro study;<o:p> </o:p>

basic research

Efficacy of the homeopathic drugs Suis and Arnica comp.-Heel® on lymphocyte and phagocyte activity

Enbergs H.

BM, 1998, 1;<o:p> </o:p>

3-11.

Effect of organotherapeutics and Arnica comp. -Heel® on immune system cells

In vitro study;<o:p> </o:p>

basic research

Influence of dilutions and potencies of cAMP on different enzymatic systems

Harisch G.,
Dittmann J.

BM, 1998, 2;<o:p> </o:p>

55-62.

Effects of dilutions and potencies of cAMP on some enzymatic activities

In vitro study;<o:p> </o:p>

basic research

Studies of the principles of homeopathy; the changeover from in vivo to in vitro experimental research

Harisch G.,
Dittmann J.

BM, 1998, 3;<o:p> </o:p>

98-103.

Potentised and non-potentised dilutions are equally effective, but have different actions

Basic research

Determination of the activity of acid phosphatase with cAMP at various potencies

Harisch G.,
Dittmann J.

BM, 1999, 1; 4-8.

Different effects on enzymatic activity

In vitro study;
basic research

Contribution to study of the efficacy of homeopathic potencies of phosphorus

Gomez J.C.

BT, 1999, 2; 53-57.

Effect of different potencies of phosphorus

Tests on guinea pigs

Determination of the activity of acid phosphatase in the presence of Ubichinon comp.

Harisch G.,
Dittmann J.

BM, 1999, 4; 188-194.

Effect of enzymatic activity of homeopathic medicine

Basic research

Biochemical efficacy of homeopathic and electronic preparations of D8 potassiumcyanate

Dittmann J.,
     Kanapin H.,
Harisch G.

FKM, 1999, 6; 15-18.

Homeopathic potentisation is more effective than electronic potentisation

Basic research

Osteoporosis in vitro in rat tibia derived osteoblasts is promoted by the homeopathic preparation, FMS Calciumfluor

Palermo C.,
     Filanti C.,
Poggi S.,
Manduca P.

Cell Biol Int, 1999,<o:p> </o:p>

23(1): 31-40.

Stimulant

Osteogenesis
     (trial with
compound drug)

Thin-layer chromatography (TLC) of homeopathic active constituents

Schmolz M.

BM, 1999, 5;<o:p> </o:p>

248-250.

Constituents of Arnica comp.- Heel® ointment: electrophoresis accelerates their skin penetration.

Basic research

Effect of homeopathic constituents on enzymatic activity.

Basic research

Efficacy of a potentised homeopathic drug in reducing cytotoxic effects produced by arsenic trioxide in mice

Datta S.,
     Mallick P.,
Khuda Bukhsh A.R.

Complement Ther
Med
, 1999Jan;
7 (8): 62-75
(a).

Protective

Arsenic trioxide
toxicity

Efficacy of a potentised homeopathic drug in reducing cytotoxic effects produced by arsenic trioxide in mice

Datta S.,
     Mallick P.,
Khuda Bukhsh A.R.

Complement Ther
Med
, 1999 Sep;
7 (3): 156-63
(b).

Protective

Arsenic trioxide
toxicity

Non-cytotoxic antiviral action of a homeopathic drug

Heine H.

Ärzteitschrift fürNeturheilverfahre, 2000; 41: 542-7.

Stimulant

ã interferon<o:p> </o:p>

synthesis

Efficacy of a potentised homeopathic drug in reducing cytotoxic effects produced by arsenic trioxide in mice

Kundu S.N.,
     Mitra K.,
Khuda Bukhsh A.R.

Complement Ther
Med
, 2000 Sep;
1 (3): 157-65.

Protective

Arsenic trioxide
toxicity

Stimulatory effect of some plant extracts used in homeopathy on the phagocytosis induced chemiluminescence of polymorphonuclear leukocytes

Crocnan D.,
     Greabu M.,
Olinescu R.

Rocz Akad Med
Biochemist
, 2000;
45: 246-254.

Stimulant

Phagocytosis

Difference between the efficacy of single potencies and chords

Dittmann J.,
Harisch G.

BM, 2000, 1; 18-23.

Potency chords are more effective than single potencies

Basic research

Influence of some homeopathic drugs on the catalytic activity of uricase, acid phosphatase and the cytosol glutathion-S-transferase

Dittmann J.,
Kanapin H.,
Harisch G.

BM, 2000, 3;<o:p> </o:p>

125-131

Effect of D8 potencies on three different enzymatic systems

Basic research

Influence of some homeopathic drugs on the catalytic activity of cAMP-dependent protein kinases

Dittmann J.,
     Kanapin H.,
Harisch G.

BM, 2000, 6;<o:p> </o:p>

289-296.

Effect of different potencies of 5 substances on enzymatic activity

Basic research

Neuroprotection from glutamate toxicity with ultra-low dose glutamate

Jonas W.,
     Lin Y.,
Zortella F.

Neuroreport,
2001 Feb 92; 12
(2): 335-9.

Protective

Glutamate toxicity

 KEY: BT = Biomedical Therapy

BM = Biologische Medizin

FKM = Forschung Komplementär Medizin

Here are some of the studies[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][35][36][35][37][38][39][40][41]

References

  1. Colas H., Aubin M., Picard P., Lebecq J.C.. "Inhibition of lymphoblast transformation test (LTT) in phytohaemagglutinin (PHA) with Phytolacca americana in homeopathic dilution". Ann. Homéopat. Fr., 1975, 6: 1-11.
  2. Mansvelt J.D., van Amons E. "Inquiry into the limits of biological effects of chemical compounds in tissue culture. I. Low dose effects of mercury chloride". Z. Naturtorschung, 1975, 30: 643-649.
  3. Poitevin B., Aubin M., Royer J.F. "The effects of Belladonna and Ferrum phosphoricum on the chemoluminescence of human poly-morphonuclear neutrophils". Ann. Homéop. Fr., 1983, 3: 5-12.
  4. Pennec J.P., Aubin M. "Effect of aconitum and veratrumon the isolated perfused heart of the common eel (Anguilla anguilla)". Comp. Biochem. Physiol., 1984, 776: 367-369.
  5. Aubin M. "Elements of homeopathic pharmacology". Homéopathie Franç., 1984, 72:231- 235
  6. Wagner H., Jurcic K., Doenicke A., Rosenhuber E., Behrens N. "The effect of homeopathic preparations on the phagocyte activity of granulocytes. In vitro tests and double-blind controlled trials". Arzneim. Forsch./Drug Res., 1986, 36: 1424-1425.
  7. Poitevin B., Aubin M., Benveniste J. "Approach to quantitative analysisof the effect of Apis mellifica on the degranulation of human basophils cultivated in vitro". Innov. Tech. Biol. Med., 1986, 7: 64-68.
  8. Wagner H., Kreher B., Jurcic K. "In vitro stimulation of human granulocytes and lymphocytes by pico- and femtogram quantities of cytostatic agents". Arzneim. Forsch./Drug Res., 1988, 38: 273-275.
  9. Davenas E., Beauvais F., Amara J., Robinson M., Miadonna A., Tedeschi A., Pomeranz B., Fortner P., Belon P., Sainte-Laudy J., Poitevin B., Benveniste J. "Human basophil degranulation triggered by very dilute antiserum against IgE". Nature, 1988, 333: 816-818.
  10. Poitevin B., Davenas E., Benveniste J. "In vitro immunologicaldegranulation of human basophilsis modulated by lung histamine and Apis mellifica". Brit. J. Clin. Pharmacol., 1988, 25: 439-444.
  11. Wagner H., Kreher B. "Cytotoxic agents as immunomodulators". Proceedings of the 3rd GIRI meeting, Paris, 1989, 31-46.
  12. Boiron J., Belon P. "Contributions of fundamental research in homeopathy". Berl. J. Res. Hom., 1990, 1: 34-35.
  13. Bornoroni C. "Synergism of action between indoleacetic acid (IAA) and highly diluted solutions of CaCO3 on the growth of oat coleoptiles". Berl. J. Res. Hom., 1991, 1 (4/5): 275-278.
  14. Boiron J., Abecassis J., Cotte J., Bernard A.M. "Study of the action of Hahnemannian dilutions of mercury chloride on the mitotic index in animal cell cultures.". Ann. Homéop.Fr., 1991, 23: 43-49.
  15. Bellavite P., Chirumbolo S., Lippi G., Andrioli G., Bonazzi L., Ferro I. "Dual effects of formylpeptides on the adhesion of endotoxin-primed human neutrophils". Cell. Biochem. Funct., 1993, 11: 231-239
  16. Chirumbolo S., Signorini A., Bianchi I., Lippi G., Bellavite P. "Effects of homeopathic preparations of organic acids and of minerals on the oxidative metabolism of human neutrophils". Br. Hom. J., 1993, 82: 227-244.
  17. Doutremepuich C., Lalanne M.C., Ramboer I., Sertillanges M.N., De Seze O. "Platelets/endothelial cells interactions in presence of acetylsalicylic acid at ultra low dose". Omeomed 92 (C. Bornoroni, ed.), 1993, Editrice Compositori, Bologna: 109-115.
  18. Fougeray S., Moubry K., Vallot N., Bastide M. "Effect of high dilutions of epidermal growth factor (EGF) on in vitro proliferation of keratinocyte and fibroblast cell lines". Br. Hom. J., 1993, 82: 124-125.
  19. Enbergs H., Arndt G. "Effects of different homeopathic potencies of Lachesis on lymphocyte cultures obtained from rabbit blood". Biol. Tier., 1993, 4.
  20. Gibson S.L., Gibson R.G. "The effect of homeopathic potencies of house dust mite on the migration of house-dust sensitive human leukocytes". Complement. Ther. Med., 1996, 4: 169-171.
  21. Kanui T.I., Enbergs H. "The effects of Nux vomica, Homaccord and Atropinum comp. on intestinal activity in vitro". Biol. Tier., 1996/1, 43-47
  22. Sainte-Laudy J., Belon P. "Application of flow cytometry to the analysis of the immunosuppressive effect of histamine dilutions on human basophil action: effect of cimetidine". Inflamm. Res., 1997, 46: S27-S28.
  23. Chirumbolo S., Conforti A., Lussignoli S., Metelmann H. et Al. "Effects of Podophyllum peltatum compounds in various preparations and dilutions on human neutrophil functions in vitro". Br. Hom. J., 1997; 86-16.
  24. Harisch G., Dittmann J. "In vivo and in vitro studies on the efficiency of potentized and nonpotentized substances". BT, 1997, 2; 40-46.
  25. Harisch G., Dittmann J. "Experiments with the effects of Ubichinon-Injeel and strong Ubichinon-Injeel on an acellular system". BM, 1997, 3; 99-104.
  26. Enbergs H. "Efficacy of the homeopathic drugs Suis and Arnica comp.-Heel® on lymphocyte and phagocyte activity". BM, 1998, 1; 3-11.
  27. Harisch G., Dittmann J. "Influence of dilutions and potencies of cAMP on different enzymatic systems". BM, 1998, 2; 55-62.
  28. Harisch G., Dittmann J. "Studies of the principles of homeopathy; the change over from in vivo to in vitro experimental research". BM, 1998, 2; 55-62.
  29. Harisch G., Dittmann J. "Determination of the activity of acid phosphatase with cAMP at various potencies". BM, 1999, 1; 4-8.
  30. Gomez J.C. "Contribution to study of the efficacy of homeopathic potencies of phosphorus". BT, 1999, 2; 53-57.
  31. Harisch G., Dittmann J. "Determination of the activity of acid phosphatase in the presence of Ubichinon comp.". BM, 1999, 4; 188-194.
  32. Dittmann J., Kanapin H., Harisch G. "Biochemical efficacy of homeopathic and electronic preparations of D8 potassium cyanate". FKM, 1999, 6; 15-18.
  33. Palermo C., Filanti C., Poggi S., Manduca P. "Osteoporosis in vitro in rat tibia derived osteoblasts is promoted by the homeopathic preparation, FMS Calciumfluor". Cell Biol Int, 1999, 23(1): 31-40.
  34. Schmolz M. "Thin-layer chromatography (TLC)of homeopathic active constituents". BM, 1999, 5; 248-250.
  35. 35.0 35.1 35.2 Datta S., Mallick P., Khuda Bukhsh A.R. "Efficacy of a potentised homeopathic drug in reducing cytotoxic effects produced by arsenic trioxide in mice". Complement Ther Med, 1999Jan; 7 (8): 62-75 (a). Cite error: Invalid <ref> tag; name "Efficacy of a potentised homeopathic drug in reducing cytotoxic effects produced by arsenic trioxide in mice" defined multiple times with different content Cite error: Invalid <ref> tag; name "Efficacy of a potentised homeopathic drug in reducing cytotoxic effects produced by arsenic trioxide in mice" defined multiple times with different content
  36. Heine H. "Non-cytotoxic antiviral action of a homeopathic drug". Ärzteitschrift fürNeturheilverfahre, 2000; 41: 542-7.
  37. Crocnan D., Greabu M., Olinescu R. "Stimulatory effect of some plant extracts used in homeopathy on the phagocytosis induced chemiluminescence of polymorphonuclear leukocytes". Rocz Akad Med Biochemist, 2000; 45: 246-254.
  38. Dittmann J., Harisch G. "Difference between the efficacy of single potencies and chords". BM, 2000, 1; 18-23.
  39. Dittmann J., Kanapin H., Harisch G. "Influence of some homeopathic drugs on the catalytic activity of uricase, acid phosphatase and thecytosol glutathion-S-transferase". BM, 2000, 3; 125-131
  40. Dittmann J., Kanapin H., Harisch G. "Influence of some homeopathic drugs on the catalytic activity of cAMP-dependent protein kinases". BM, 2000, 6; 289-296.
  41. Jonas W., Lin Y., Zortella F. "Neuroprotection from glutamatetoxicity with ultra-low dose glutamate". Neuroreport, 2001 Feb 92; 12 (2): 335-9.