Monoclonal antibody: Difference between revisions
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imported>Howard C. Berkowitz (New page: A '''monoclonal antibody''' is an immune substance "produced by clones of cells such as those isolated after hybridization of activated B-lymphocytes with neop...) |
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A '''monoclonal antibody''' is an immune substance "produced by clones of cells such as those isolated after hybridization of activated [[Lymphocyte#B-lymphocyte|B-lymphocyte]]s with neoplastic cells. These hybrids are often referred to as [[hybridomas]]." <ref>{{MeSH|Antibody, monoclonal}}</ref> Monoclonal antibodies have extensive applications in clinical medicine and immunochemistry. | A '''monoclonal antibody''' is an immune substance "produced by clones of cells such as those isolated after hybridization of activated [[Lymphocyte#B-lymphocyte|B-lymphocyte]]s with neoplastic cells. These hybrids are often referred to as [[hybridomas]]." <ref>{{MeSH|Antibody, monoclonal}}</ref> Monoclonal antibodies have extensive applications in clinical medicine and immunochemistry. | ||
Revision as of 08:38, 5 February 2009
A monoclonal antibody is an immune substance "produced by clones of cells such as those isolated after hybridization of activated B-lymphocytes with neoplastic cells. These hybrids are often referred to as hybridomas." [1] Monoclonal antibodies have extensive applications in clinical medicine and immunochemistry.
The World Health Organization is refining naming conventions for monoclonal antibodies. [2] Its original system came from the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) Biotech Working Group.[3]
References
- ↑ Anonymous (2024), Antibody, monoclonal (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Anna-Maija Autere, Nicole Wagner and Georg-Burkhard Kresse from Roche on behalf of International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) Biotech Working Group (2008), "International Nonproprietary Names for monoclonal antibodies: IFPMA proposal", WHO Drug Information 22 (2), pp. 97-107
- ↑ International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) Biotech Working Group (2008), [http://www.ifpma.org/fileadmin/templates/ifpmaissues/pdfs/2008_03_21_IFPMA_Proposal_for_naming_of_new_monoclonals.pdf Proposal to the WHO INN Expert Group: Principles for naming of new monoclonal antibodies]