Amprenavir: Difference between revisions
Jump to navigation
Jump to search
imported>David E. Volk mNo edit summary |
imported>David E. Volk mNo edit summary |
||
| Line 2: | Line 2: | ||
[[Image:Amprenavir structure.jpg|right|thumb|200px|{{#ifexist:Template:Amprenavir structure.jpg/credit|{{Amprenavir structure.jpg/credit}}<br/>|}}Amprenavir.]] | [[Image:Amprenavir structure.jpg|right|thumb|200px|{{#ifexist:Template:Amprenavir structure.jpg/credit|{{Amprenavir structure.jpg/credit}}<br/>|}}Amprenavir.]] | ||
'''Amprenavir''', also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- | '''Amprenavir''', also called AMP, AMV, APV and VX-478, is a [[protease inhibitor]] used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- | ||
hydroxy-1-phenylbutan-2-yl]carbamate. | hydroxy-1-phenylbutan-2-yl]carbamate. | ||
Revision as of 19:37, 28 January 2008
Amprenavir, also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- hydroxy-1-phenylbutan-2-yl]carbamate.
Brand Names
- Agenerase®
- Prozei®
- Vertex®
External Links
- Amprenavir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Drug Bank at http://www.drugbank.ca/cgi-bin/getCard.cgi?CARD=DB00701