Amprenavir: Difference between revisions
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imported>David E. Volk (Chem infobox) |
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[[Image:Amprenavir structure.jpg|right|thumb|200px|{{#ifexist:Template:Amprenavir structure.jpg/credit|{{Amprenavir structure.jpg/credit}}<br/>|}}Amprenavir.]] | |||
{{Chem infobox | |||
|align=right | |||
|image=[[Image:Amprenavir structure.jpg|right|thumb|200px|{{#ifexist:Template:Amprenavir structure.jpg/credit|{{Amprenavir structure.jpg/credit}}<br/>|}}Amprenavir.]] | |||
|width=200px | |||
|molname=amprenavir | |||
|synonyms= AMP, AMV, APV, VX-478 | |||
|molformula= C<sub>25</sub>H<sub>35</sub>N<sub>3</sub>O<sub>6</sub>S | |||
|molmass= 505.6269 | |||
|uses=HIV | |||
|properties=protease inhibitor | |||
|hazards=see drug interactions | |||
|iupac= see chemistry section | |||
|casnumber= 161814-49-9 | |||
}} | |||
'''Amprenavir''', also called AMP, AMV, APV and VX-478, is a [[protease inhibitor]] used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- | '''Amprenavir''', also called AMP, AMV, APV and VX-478, is a [[protease inhibitor]] used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- | ||
Revision as of 08:52, 22 March 2008
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| amprenavir | |||||||
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| Uses: | HIV | ||||||
| Properties: | protease inhibitor | ||||||
| Hazards: | see drug interactions | ||||||
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Amprenavir, also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-
hydroxy-1-phenylbutan-2-yl]carbamate.
Brand Names
- Agenerase®
- Prozei®
- Vertex®
External Links
- Amprenavir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Template:MedMaster
- Template:DrugBank