Talk:Steroid

Naming convention

I could be wrong, but I thought the usual naming convention is to have a singular title. In this case, "Steroid". In this way, the first line would be changed to "A steroid, (or steroid hormone), is a powerful hormone with drastic effects, both good and bad, when artificially introduced into living systems." If figure if a change needs to occur, it should happen before the subpages are created. Richard Pettitt 10:30, 21 December 2007 (CST)

Ttile fixed, thank for the reminder Richard.

Also, I can't decide how much information to put on this page regarding each of the classes of steroids. At present, I think more detailed pages for each steroid, or class of steroids, is needed to detail the physiological role of each group or each particular steroid. David E. Volk 11:43, 21 December 2007 (CST)

Organization

Great start on this page. Can we change organization to something like:

==Classification==

• Corticosteroids
  • Glucocorticoids
  • Mineralcorticoids
• Sex steroids (estrogens and androgens)
• Progestagens

==Biochemistry==

• Synthesis

(put cholesterol section here)

• Mechanism of action

(put hormone receptors and mechanism of action here)

==Medical uses of steroids== (put Cortisone and Prednisone section here)

==Diseases of steroid metabolism==

• 21-hydroxylase deficiency (Congenital Adrenal Hyperplasia)

If this is ok, I am happy to take first attempt at this. - Robert Badgett 23:46, 31 December 2007 (CST)

Robert, I agree with you. I have been wondering if what I have written so far should be a subpage called steroid biosynthesis, are a section. However, I always like to see pictures of things being discussed. The health related topics should dominate the article, with the synthesis as a fill-in. Go ahead and re-write as you see fit and I will come back through the article afterwards. David E. Volk 09:24, 1 January 2008 (CST)

Done, please check some small rewordings I did at 1) from the beginning of Progestagens section I moved a sentence to the Synthesis section, 2) start of sex steroids I reversed a sentence so the links to the more specific articles would be easier to find, 3) I added a few words to the Medical uses section. - Robert Badgett 15:26, 1 January 2008 (CST)

In order for the biochemistry to flow correctly, we should probably start discussing the largest steroids first. Then the biochemistry/structures will flow in an orderly fashion. So probably, in this order

• Progestagens - start of life, pregency
• Corticosteroids - metabolism in general
  • Glucocorticoids
  • Mineralcorticoids
• Sex steroids - sexual dimorphism
  • androgens
  • estrogens

David E. Volk 14:12, 27 March 2008 (CDT)

Approval

I'd like to see this moved swiftly to Approval. I thought it lacked a bit on the history so added a section on the Nobel Prize but that could easily be moved to another article if others differ. I think it would be better for a few lines on HRT and a few lines on Contraceptive use. But basically I'm willing to support swift approval.Gareth Leng 17:15, 14 January 2009 (UTC)