Antilipemic agent: Difference between revisions
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==Uses== | ==Uses== | ||
{{main|Hypercholesterolemia|Hypoalphalipoproteinemia}} | {{main|Hypercholesterolemia|Hypoalphalipoproteinemia}} | ||
==Adverse effects== | |||
Medications, such as the antilipemic agents [[atorvastatin]], [[simvastatin]], or [[gemfibrozil]] that are metabolized by [[cytochrome P-450]] may increase bleeding when added to patients taking [[warfarin]].<ref name="pmid20103024">{{cite journal| author=Schelleman H, Bilker WB, Brensinger CM, Wan F, Yang YX, Hennessy S| title=Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk. | journal=Am J Med | year= 2010 | volume= 123 | issue= 2 | pages= 151-7 | pmid=20103024 | |||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=20103024 | doi=10.1016/j.amjmed.2009.07.020 | pmc=PMC2813204 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 19:27, 2 March 2010
In medicine, antilipemic agents are medications for the treatment of hypercholesterolemia and hypertriglyceridemia.[1]
Classification
Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins)
Bile acid sequestrants
Fibric acid derivatives
Fibric acid derivatives include gemfibrozil, clofibrate, and fenofibrate. Fenofibrate is unique in being able to lower the serum uric acid level and treat hyperuricemia.[2]
Plant stanols
Uses
Adverse effects
Medications, such as the antilipemic agents atorvastatin, simvastatin, or gemfibrozil that are metabolized by cytochrome P-450 may increase bleeding when added to patients taking warfarin.[3]
References
- ↑ Anonymous (2024), Antilipemic agent (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Feher MD, Hepburn AL, Hogarth MB, Ball SG, Kaye SA (February 2003). "Fenofibrate enhances urate reduction in men treated with allopurinol for hyperuricaemia and gout". Rheumatology (Oxford) 42 (2): 321–5. PMID 12595630. [e]
- ↑ Schelleman H, Bilker WB, Brensinger CM, Wan F, Yang YX, Hennessy S (2010). "Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk.". Am J Med 123 (2): 151-7. DOI:10.1016/j.amjmed.2009.07.020. PMID 20103024. PMC PMC2813204. Research Blogging.