Amprenavir: Difference between revisions
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imported>David E. Volk (New page: {{subpages}} right|thumb|200px|{{#ifexist:Template:Amprenavir structure.jpg/credit|{{Amprenavir structure.jpg/credit}}<br/>|}}Amprenavir. '''Amprenavir...) |
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'''Amprenavir''', also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. | '''Amprenavir''', also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- | ||
hydroxy-1-phenylbutan-2-yl]carbamate. | |||
== Brand Names == | == Brand Names == | ||
Revision as of 18:33, 25 January 2008
Amprenavir, also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- hydroxy-1-phenylbutan-2-yl]carbamate.
Brand Names
- Agenerase®
- Prozei®
- Vertex®
External Links
- Amprenavir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Drug Bank at http://www.drugbank.ca/cgi-bin/getCard.cgi?CARD=DB00701