MELD Score: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>Robert Badgett
No edit summary
imported>Robert Badgett
Line 21: Line 21:
The MELD has also been studied in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS).<ref name="pmid10733541">{{cite journal |author=Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J, ter Borg PC |title=A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts |journal=Hepatology |volume=31 |issue=4 |pages=864–71 |year=2000 |pmid=10733541 |doi=10.1053/he.2000.5852}}</ref>
The MELD has also been studied in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS).<ref name="pmid10733541">{{cite journal |author=Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J, ter Borg PC |title=A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts |journal=Hepatology |volume=31 |issue=4 |pages=864–71 |year=2000 |pmid=10733541 |doi=10.1053/he.2000.5852}}</ref>


In [[preoperative care]], the [[MELD Score]] can help predict complications of surgery among patients with [[cirrhosis]].<ref name="pmid17408652">{{cite journal |author=Teh SH, Nagorney DM, Stevens SR, ''et al'' |title=Risk factors for mortality after surgery in patients with cirrhosis |journal=Gastroenterology |volume=132 |issue=4 |pages=1261–9 |year=2007 |month=April |pmid=17408652 |doi=10.1053/j.gastro.2007.01.040 |url=http://linkinghub.elsevier.com/retrieve/pii/S0016-5085(07)00179-5 |issn=}}</ref> The MELD Score may <ref name="pmid15546574">{{cite journal |author=Farnsworth N, Fagan SP, Berger DH, Awad SS |title=Child-Turcotte-Pugh versus MELD score as a predictor of outcome after elective and emergent surgery in cirrhotic patients |journal=Am. J. Surg. |volume=188 |issue=5 |pages=580–3 |year=2004 |month=November |pmid=15546574 |doi=10.1016/j.amjsurg.2004.07.034 |url=http://linkinghub.elsevier.com/retrieve/pii/S0002-9610(04)00367-8 |issn=}}</ref> or may not<ref name="pmid15290666">{{cite journal |author=Suman A, Barnes DS, Zein NN, Levinthal GN, Connor JT, Carey WD |title=Predicting outcome after cardiac surgery in patients with cirrhosis: a comparison of Child-Pugh and MELD scores |journal=Clin. Gastroenterol. Hepatol. |volume=2 |issue=8 |pages=719–23 |year=2004 |month=August |pmid=15290666 |doi= |url= |issn=}}</ref> perform better than the Child-Turcotte-Pugh class.
In [[preoperative care]], the [[MELD Score]] can help predict complications of surgery among patients with [[cirrhosis]].<ref name="pmid17408652">{{cite journal |author=Teh SH, Nagorney DM, Stevens SR, ''et al'' |title=Risk factors for mortality after surgery in patients with cirrhosis |journal=Gastroenterology |volume=132 |issue=4 |pages=1261–9 |year=2007 |month=April |pmid=17408652 |doi=10.1053/j.gastro.2007.01.040 |url=http://linkinghub.elsevier.com/retrieve/pii/S0016-5085(07)00179-5 |issn=}}</ref> The MELD Score may <ref name="pmid15546574">{{cite journal |author=Farnsworth N, Fagan SP, Berger DH, Awad SS |title=Child-Turcotte-Pugh versus MELD score as a predictor of outcome after elective and emergent surgery in cirrhotic patients |journal=Am. J. Surg. |volume=188 |issue=5 |pages=580–3 |year=2004 |month=November |pmid=15546574 |doi=10.1016/j.amjsurg.2004.07.034 |url=http://linkinghub.elsevier.com/retrieve/pii/S0002-9610(04)00367-8 |issn=}}</ref> or may not<ref name="pmid15290666">{{cite journal |author=Suman A, Barnes DS, Zein NN, Levinthal GN, Connor JT, Carey WD |title=Predicting outcome after cardiac surgery in patients with cirrhosis: a comparison of Child-Pugh and MELD scores |journal=Clin. Gastroenterol. Hepatol. |volume=2 |issue=8 |pages=719–23 |year=2004 |month=August |pmid=15290666 |doi= |url= |issn=}}</ref> perform better than the [[Child-Pugh Score|Child-Turcotte-Pugh classification]].


==References==
==References==

Revision as of 06:19, 10 November 2008

This article is developing and not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.

The MELD score can help predict mortality in patients with cirrhosis and end-stage liver disease.

Calculation

The equation is:

An online calculator is available.

Adding the serum sodium to the calculation may improve accuracy.[1]

Interpretation

In interpeting the MELD Score in hospitalized patients, the 3 month mortality is:[2]

  • 40 or more - 100% mortality
  • 30-39 - 83% mortality
  • 20-29 - 76% mortality
  • 10-19 - 27% mortality
  • <10 - 4% mortality

The MELD has also been studied in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS).[3]

In preoperative care, the MELD Score can help predict complications of surgery among patients with cirrhosis.[4] The MELD Score may [5] or may not[6] perform better than the Child-Turcotte-Pugh classification.

References

  1. Kim WR, Biggins SW, Kremers WK, et al (September 2008). "Hyponatremia and mortality among patients on the liver-transplant waiting list". N. Engl. J. Med. 359 (10): 1018–26. DOI:10.1056/NEJMoa0801209. PMID 18768945. Research Blogging.
  2. Kamath PS, Wiesner RH, Malinchoc M, et al (2001). "A model to predict survival in patients with end-stage liver disease". Hepatology 33 (2): 464–70. DOI:10.1053/jhep.2001.22172. PMID 11172350. Research Blogging.
  3. Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J, ter Borg PC (2000). "A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts". Hepatology 31 (4): 864–71. DOI:10.1053/he.2000.5852. PMID 10733541. Research Blogging.
  4. Teh SH, Nagorney DM, Stevens SR, et al (April 2007). "Risk factors for mortality after surgery in patients with cirrhosis". Gastroenterology 132 (4): 1261–9. DOI:10.1053/j.gastro.2007.01.040. PMID 17408652. Research Blogging.
  5. Farnsworth N, Fagan SP, Berger DH, Awad SS (November 2004). "Child-Turcotte-Pugh versus MELD score as a predictor of outcome after elective and emergent surgery in cirrhotic patients". Am. J. Surg. 188 (5): 580–3. DOI:10.1016/j.amjsurg.2004.07.034. PMID 15546574. Research Blogging.
  6. Suman A, Barnes DS, Zein NN, Levinthal GN, Connor JT, Carey WD (August 2004). "Predicting outcome after cardiac surgery in patients with cirrhosis: a comparison of Child-Pugh and MELD scores". Clin. Gastroenterol. Hepatol. 2 (8): 719–23. PMID 15290666[e]

External links