Talk:Oxytocin/Draft

Wikipedia credit

The following text appears to come from Wikipedia. What about some nice rewording to assure that no WP-credit is needed? Here it goes:

• The sequence is cysteine - tyrosine - isoleucine - glutamine - asparagine - cysteine - proline - leucine - glycine (CYIQNCPLG).
• The cysteine residues form a sulfur bridge.
• The two genes are always located close to each other (less than 15,000 bases apart) on the same chromosome and are transcribed in opposite directions.
• It belongs to the rhodopsin-type (class I) group of G-protein-coupled receptors.
• Uterine contraction - important for cervical dilation before birth and causes contractions during the second and third stages of labor.
• Actions of oxytocin within the brain.
• Drugs administered by nasal spray are thought to have better access to the CNS.
• It has fewer side-effects than drugs previously used for this purpose (ritodrine, salbutamol and terbutaline).

--AlekStos 15:04, 28 March 2007 (CDT)

I don't see a need to make changes for changes sake. Some us spent a lot of time on the WP article so we liked what it said (at least in parts!). Modifications that make it better are welcome, of course. Some of what you have pointed out above is not correct, however, and should be modified (thanks). For example, the genes are not always that close if you include homologs as in Fugu. There is no good evidence that Oxt has access to the CNS via intranasal application, despite claims from some. Thank you! - ScottYoung 15:18, 28 March 2007 (CDT)

Well done article on Oxytocin

Thorough treatment of subject, a challenging study for an undergraduate or medical student, which could be made less so with more referencing of the assertions you make throughout.

The excellent summary in the lede has no source citations. Consider citing the Caldwell book given in the Bibliography subpage, as supporting the lede. Perhaps one or two more such general reviews of oxytocin (review articles, or other books) could also be cited in lede.

You might also consider noting that oxytocin might have effects on the developing fetus that lead to lifelong social behavioral effects – fetal programming. See: doi:10.1016/S0031-9384(03)00151-3.

I would be happy to nominate the article for approval whenever you’d like. Anthony.Sebastian 18:00, 10 November 2010 (UTC)

Re 'eutherian'

Wondering whether a note defining 'eutherian' would help the reader. Anthony.Sebastian 07:07, 15 November 2010 (UTC)