Salsalate

From Citizendium
Revision as of 00:45, 6 January 2011 by imported>Robert Badgett
Jump to navigation Jump to search

In pharmacology, salsalate, also called salicylsalicylic acid and disalicylic acid, is a medication which is a non-steroidal anti-inflammatory agent. Salsalate is related to acetylsalicylic acid (aspirin), but unlike acetylsalicylic acid, salsalate does not irreversibly inhibit cyclooxygenase and thus is not an anti-platelet agent.

Salsalate may reduce the Glycosylated hemoglobin A1c in patients with diabetes mellitus type 2.[1]

Drug toxicity

Tinnitus may happen, but is unlikely if the total daily dose is 3 grams or less.[1]

References

  1. 1.0 1.1 Goldfine AB, Fonseca V, Jablonski KA, Pyle L, Staten MA, Shoelson SE et al. (2010). "The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial.". Ann Intern Med 152 (6): 346-57. DOI:10.1059/0003-4819-152-6-201003160-00004. PMID 20231565. Research Blogging. Cite error: Invalid <ref> tag; name "pmid20231565" defined multiple times with different content