Hypertriglyceridemia
In medicine hypertriglyceridemia is a dyslipidemia and is "a condition of elevated levels of triglycerides in the blood".[1]
One cause is hypoalphalipoproteinemia.
Treatment
Clinical practice guidelines state:[2] "Patients in whom triglycerides >500 mg/dL should receive strict diet therapy including avoidance of alcohol, restriction of dietary fat, and avoidance of concentrated carbohydrates (sweets). For triglycerides >1000 mg/dL a very low fat diet should be instituted quickly to reduce chylomicronemia and risk of acute pancreatitis"
More recently, "the combination of fenofibrate and simvastatin did not reduce the rate of fatal cardiovascular events, nonfatal myocardial infarction, or nonfatal stroke, as compared with simvastatin alone" according to a randomized controlled trial. [3]
References
- ↑ Anonymous (2024), Hypertriglyceridemia (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ [Management of Dyslipidemia Working Group. VA/DoD clinical practice guideline for the management of dyslipidemia. Washington (DC): Department of Veterans Affairs, Department of Defense; 2006. 140 p.
- ↑ ACCORD Study Group. Ginsberg HN, Elam MB, Lovato LC, Crouse JR, Leiter LA et al. (2010). "Effects of combination lipid therapy in type 2 diabetes mellitus.". N Engl J Med 362 (17): 1563-74. PMID 20228404.