File:Blood-brain barrier schematic.png
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Summary
| Title / Description
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Schematic drawing of cellular regulation of extracellular glutamate concentrations ([Glu]ec) in normal brain function. Two neuronal cell bodies with processes (white) make contact with each other through a synapse (center). Astrocytic (pink) processes encapsulate the synapse and cover also the abluminal side of the blood vessel wall (right). The endothelial cells covering the luminal (blood) side of the vessel wall and the astrocytic processes make up the blood brain barrier (BBB). An oligodendroglial cell (bluish), with its myelin encapsulating the axon, and a microglial cell (yellow) are seen. The astrocytes, with their high-affinity glutamate transporters, are the main site for keeping [Glu]ec low. Even neurons express glutamate transporters, as do oligodendroglial cells, and endothelial cells at their abluminal side. |
|---|---|
| Author(s)
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Rönnbäck and Hansson, 2004 |
| Copyright holder
|
Rönnbäck and Hansson, 2004 See below for license/re-use information. |
| Source
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Part of Fig. 1 from Rönnbäck L, Hansson E (2004). "On the potential role of glutamate transport in mental fatigue". J Neuroinflammation 1 (1): 22. DOI:10.1186/1742-2094-1-22. PMID 15527505. PMC PMC533886. Research Blogging. [e] |
| Date created
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30 August 2004 |
| Country of first publication
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United States |
| Notes
|
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| Other versions
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Image:Blood-brain barrier and proinflammatory cytokines.png |
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