APP/Bibliography

A list of key readings about APP.

• Beyreuther K, Pollwein P, Multhaup G, et al. (1993). "Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome.". Ann. N. Y. Acad. Sci. 695: 91-102. PMID 8239320. ^[e]

• Janciauskiene S, Wright HT (1999). "Inflammation, antichymotrypsin, and lipid metabolism: autogenic etiology of Alzheimer's disease.". Bioessays 20 (12): 1039-46. DOI:<1039::AID-BIES10>3.0.CO;2-Z 10.1002/(SICI)1521-1878(199812)20:12<1039::AID-BIES10>3.0.CO;2-Z. PMID 10048303. <1039::AID-BIES10>3.0.CO;2-Z Research Blogging.

• Kontush A (2002). "Alzheimer's amyloid-beta as a preventive antioxidant for brain lipoproteins.". Cell. Mol. Neurobiol. 21 (4): 299-315. PMID 11775062. ^[e]

• Blennow K, Vanmechelen E, Hampel H (2002). "CSF total tau, Abeta42 and phosphorylated tau protein as biomarkers for Alzheimer's disease.". Mol. Neurobiol. 24 (1-3): 87-97. PMID 11831556. ^[e]

• Yanagisawa K (2002). "[Pathological implications of GM1 ganglioside-bound amyloid beta-protein in Alzheimer's disease]". Tanpakushitsu Kakusan Koso 47 (4 Suppl): 344-50. PMID 11915325. ^[e]

• Matsuzaki K (2002). "[Interactions between amyloid beta--protein and gangliosides]". Tanpakushitsu Kakusan Koso 47 (4 Suppl): 351-6. PMID 11915326. ^[e]

• Bush AI, Tanzi RE (2002). "The galvanization of beta-amyloid in Alzheimer's disease.". Proc. Natl. Acad. Sci. U.S.A. 99 (11): 7317-9. DOI:10.1073/pnas.122249699. PMID 12032279. Research Blogging.

• Doré S (2002). "Decreased activity of the antioxidant heme oxygenase enzyme: implications in ischemia and in Alzheimer's disease.". Free Radic. Biol. Med. 32 (12): 1276-82. PMID 12057765. ^[e]

• Straub JE, Guevara J, Huo S, Lee JP (2003). "Long time dynamic simulations: exploring the folding pathways of an Alzheimer's amyloid Abeta-peptide.". Acc. Chem. Res. 35 (6): 473-81. PMID 12069633. ^[e]

• Annaert W, De Strooper B (2003). "A cell biological perspective on Alzheimer's disease.". Annu. Rev. Cell Dev. Biol. 18: 25-51. DOI:10.1146/annurev.cellbio.18.020402.142302. PMID 12142279. Research Blogging.

• Koo EH (2003). "The beta-amyloid precursor protein (APP) and Alzheimer's disease: does the tail wag the dog?". Traffic 3 (11): 763-70. PMID 12383342. ^[e]

• Van Nostrand WE, Melchor JP, Romanov G, et al. (2003). "Pathogenic effects of cerebral amyloid angiopathy mutations in the amyloid beta-protein precursor.". Ann. N. Y. Acad. Sci. 977: 258-65. PMID 12480759. ^[e]

• Ling Y, Morgan K, Kalsheker N (2004). "Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease.". Int. J. Biochem. Cell Biol. 35 (11): 1505-35. PMID 12824062. ^[e]

• Kerr ML, Small DH (2005). "Cytoplasmic domain of the beta-amyloid protein precursor of Alzheimer's disease: function, regulation of proteolysis, and implications for drug development.". J. Neurosci. Res. 80 (2): 151-9. DOI:10.1002/jnr.20408. PMID 15672415. Research Blogging.

• Maynard CJ, Bush AI, Masters CL, et al. (2005). "Metals and amyloid-beta in Alzheimer's disease.". International journal of experimental pathology 86 (3): 147-59. DOI:10.1111/j.0959-9673.2005.00434.x. PMID 15910549. Research Blogging.

• Tickler AK, Wade JD, Separovic F (2005). "The role of Abeta peptides in Alzheimer's disease.". Protein Pept. Lett. 12 (6): 513-9. PMID 16101387. ^[e]

• Reinhard C, Hébert SS, De Strooper B (2006). "The amyloid-beta precursor protein: integrating structure with biological function.". EMBO J. 24 (23): 3996-4006. DOI:10.1038/sj.emboj.7600860. PMID 16252002. Research Blogging.

• Watson D, Castaño E, Kokjohn TA, et al. (2006). "Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.". Neurol. Res. 27 (8): 869-81. DOI:10.1179/016164105X49436. PMID 16354549. Research Blogging.

• Calinisan V, Gravem D, Chen RP, et al. (2006). "New insights into potential functions for the protein 4.1 superfamily of proteins in kidney epithelium.". Front. Biosci. 11: 1646-66. PMID 16368544. ^[e]

• Vetrivel KS, Thinakaran G (2006). "Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments.". Neurology 66 (2 Suppl 1): S69-73. DOI:10.1212/01.wnl.0000192107.17175.39. PMID 16432149. Research Blogging.

• Gallo C, Orlassino R, Vineis C (2006). "[Recurrent intraparenchimal haemorrhages in a patient with cerebral amyloidotic angiopathy: description of one autopsy case]". Pathologica 98 (1): 44-7. PMID 16789686. ^[e]

• Coulson EJ (2006). "Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease?". J. Neurochem. 98 (3): 654-60. DOI:10.1111/j.1471-4159.2006.03905.x. PMID 16893414. Research Blogging.

• Menéndez-González M, Pérez-Pinera P, Martínez-Rivera M, et al. (2006). "APP processing and the APP-KPI domain involvement in the amyloid cascade.". Neuro-degenerative diseases 2 (6): 277-83. DOI:10.1159/000092315. PMID 16909010. Research Blogging.

• Neve RL, McPhie DL (2007). "Dysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosis.". Biochim. Biophys. Acta 1772 (4): 430-7. DOI:10.1016/j.bbadis.2006.10.008. PMID 17113271. Research Blogging.

• Chen X, Stern D, Yan SD (2007). "Mitochondrial dysfunction and Alzheimer's disease.". Current Alzheimer research 3 (5): 515-20. PMID 17168650. ^[e]

• Caltagarone J, Jing Z, Bowser R (2007). "Focal adhesions regulate Abeta signaling and cell death in Alzheimer's disease.". Biochim. Biophys. Acta 1772 (4): 438-45. DOI:10.1016/j.bbadis.2006.11.007. PMID 17215111. Research Blogging.

• Wolfe MS (2007). "When loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking Point on the role of presenilin mutations in Alzheimer disease.". EMBO Rep. 8 (2): 136-40. DOI:10.1038/sj.embor.7400896. PMID 17268504. Research Blogging.