Central dogma of molecular genetics

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The central dogma of molecular biology refers to the concept put forward by Francis Crick that information flow in the cell goes from DNA to messenger RNA to protein.


"My mind was, that a dogma was an idea for which there was no resonable evidence" [1] (Francis Crick)

Famously, Crick seems to have misunderstood the precise meaning of the word dogma whem formulating his brilliant hypothesis of how the genetic code of genes is used in cells during synthesis of proteins to determine via RNA intermediates the order of amino acid residues in proteins.

References

  1. ↑ See discussion in Chapter 7. Horace Freeland Judson (1979). The Eight Day of Creation: Makers of the Revolution in Molecular Biology. ISBN 0140178007.
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