File:CO2-O2-fMRI-A-left.png

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Summary

Title / Description


Functional magnetic resonance imaging of the human brain during gas challenges. Instead of normal air, the participants inhaled either pure oxygen (hyperoxia condition), or 95% oxygen and 5% carbon dioxide (hypercapnic hyperoxia). Yellow (hyperoxia) and green (hypercapnic hyperoxia) overlays of regions of significant signal response in 14 children at any of five time successive periods during the challenges. Multiple brain regions responded to hyperoxia, but the addition of 5% O2 by CO2 greatly reduced most responses. Statistical threshold p = 0.05, false discovery rate correction. The background image is a high-resolution scan from a single participant (normalized to Montreal Neurological Institute space).
Author(s)


Macey et al., 2007
Copyright holder


Macey et al., 2007
See below for license/re-use information.
Source


Fig. 1 from Macey PM, Woo MA, Harper RM (2007). "Hyperoxic brain effects are normalized by addition of CO2". PLoS Med 4 (5): e173. DOI:10.1371/journal.pmed.0040173. PMID 17518514. PMC PMC1872042. Research Blogging[e]
Date created


June 26, 2006
Country of first publication


United States
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current19:57, 11 March 2022Thumbnail for version as of 19:57, 11 March 20222,808 × 1,951 (230 KB)Maintenance script (talk | contribs)== Summary == Importing file

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