Carboplatin

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In oncology, carboplatin is an "organoplatinum compound that possesses antineoplastic activity."[1]

History

In the United States, it was approved with a New Drug Application (NDA) by the FDA in 1989.[2] A generic version was approved with a Abbreviated New Drug Application (ANDA) in 2003.[3]

As compared to cisplatin, carboplatin has equal (lung cancer, ovarian cancer) or less (germ cell tumors, bladder cancer, head and neck cancer) efficacy but less drug toxicity.[4]

External links

The most up-to-date information about Carboplatin and other drugs can be found at the following sites.


References

  1. Anonymous (2024), Carboplatin (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Drugs@FDA. U S Food and Drug Administration
  3. Drugs@FDA. U S Food and Drug Administration
  4. Lokich J, Anderson N (1998). "Carboplatin versus cisplatin in solid tumors: an analysis of the literature.". Ann Oncol 9 (1): 13-21. PMID 9541678.