Cholinesterase inhibitor

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Revision as of 08:13, 10 April 2009 by imported>Robert Badgett (New page: In medicine, '''cholinesterase inhibitors''' are "drugs that inhibit cholinesterases. The neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by chol...)
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In medicine, cholinesterase inhibitors are "drugs that inhibit cholinesterases. The neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system."[1]

Cholinesterase inhibitors may stimulate the parasympathetic nervous system.

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