Uracil

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Revision as of 09:38, 19 June 2008 by imported>David E. Volk
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Citable Version  [?]
 
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Uracil.jpg
uracil
IUPAC name:
Synonyms:
Formula: C4H4N2O2

 Uses: RNA base

 Properties:

 Hazards:

Mass (g/mol): CAS #:


Uracil is one of the bases found in RNA. In RNA, the H1 proton is removed and the N1-nitrogen atom is bound the the C1' carbon of ribose. It is analogous in structure to thymidine, which can be thought of as 5-methyl-uracil, and it usually forms base pairs with adenine (A) in RNA. In an adenine-uracil base pair, the O4 oxygen atom of uracil forms a hydrogen bond with one of the amino protons (H61) of adenine. A second hydrogen bond is formed between the uracil H3 proton and the adenine N1 nitrogen atom. Like other nucleotide bases, it is subject to oxidative damage.