Platelet aggregation inhibitors

Platelet aggregation inhibitors, also called antiplatelet drugs, are "drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system."

Classification

Adenosine diphosphate (ADP) blocker

This includes dipyrimadole.

Cyclooxygenase-1 blockers

Cyclooxygenase-1 blockers include aspirin.

Glycoprotein IIb/IIIa inhibitors

Inhibitors of the platelet glycoprotein GPIIb-IIIa complex include eptifibatide, tirofiban, and the monoclonal antibody abciximab.

Thienopyridines

Thienopyridines include clopidogrel, ticlopidine, and the prodrug prasugrel.