Allergic rhinitis

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Allergic rhinitis, also called seasonal allergic rhinitis is defined as "rhinitis that occurs at the same time every year. It is characterized by acute conjunctivitis with lacrimation and itching, and regarded as an allergic condition triggered by specific allergens."[1]

Cause / etiology

Allergic rhinitis may be associated with bronchial hyperreactivity.[2]

Diagnosis

Treatment

Clinical practice guidelines by written by authors with conflict of interests address the treatment.[3]

Among alpha adrenergic receptor agonists, pseudoephedrine may be better than phenylephrine in the improvement of nasal congestion.[4]

Combination treatment

Azelastine nasal spray and fluticasone nasal spray in combination may be more effective than either used alone according to a randomized controlled trial.[5] However, mometasone monotherapy may be as effective as mometasone combined with loratadine.[6]

References

  1. National Library of Medicine. Allergic rhinitis. Retrieved on 2007-11-08.
  2. Shaaban R, Zureik M, Soussan D, et al (2007). "Allergic rhinitis and onset of bronchial hyperresponsiveness: a population-based study". Am. J. Respir. Crit. Care Med. 176 (7): 659–66. DOI:10.1164/rccm.200703-427OC. PMID 17615387. Research Blogging.
  3. Wallace DV, Dykewicz MS, Bernstein DI, et al (August 2008). "The diagnosis and management of rhinitis: an updated practice parameter". J. Allergy Clin. Immunol. 122 (2 Suppl): S1–84. DOI:10.1016/j.jaci.2008.06.003. PMID 18662584. Research Blogging.
  4. Horak F, Zieglmayer P, Zieglmayer R, et al (February 2009). "A placebo-controlled study of the nasal decongestant effect of phenylephrine and pseudoephedrine in the Vienna Challenge Chamber". Ann. Allergy Asthma Immunol. 102 (2): 116–20. PMID 19230461[e]
  5. Ratner PH, Hampel F, Van Bavel J, et al (2008). "Combination therapy with azelastine hydrochloride nasal spray and fluticasone propionate nasal spray in the treatment of patients with seasonal allergic rhinitis". Ann. Allergy Asthma Immunol. 100 (1): 74–81. PMID 18254486[e]
  6. Anolik R, Mometasone Furoate Nasal Spray With Loratadine Study Group (2008). "Clinical benefits of combination treatment with mometasone furoate nasal spray and loratadine vs monotherapy with mometasone furoate in the treatment of seasonal allergic rhinitis.". Ann Allergy Asthma Immunol 100 (3): 264-71. PMID 18426147.

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