Hemolytic anemia

From Citizendium
Revision as of 23:54, 21 December 2014 by imported>Robert Badgett (Classification)
Jump to navigation Jump to search

In hematology, Hemolytic anemia is an "A condition of inadequate circulating red blood cells (anemia) or insufficient hemoglobin due to premature destruction of red blood cells (erythrocytes)."[1]

Classification

One classification is based on whether hemolysis occurs intravascularly or extravascularly. Another classification is whether the erythrocytes are intrinsically normal:[2]

Hemolytic anemia associated with normal red cells

  • Autoimmune hemolytic anemia
  • Complement-induced lysis
  • Microangiopathic hemolytic anemia

Hemolytic anemia associated with abnormal red cells

  • Hemoglobinopathies
  • Metabolic deficiency
  • Erythrocyte membrane abnormality

Diagnosis

References