Mevastatin/Related Articles

See also changes related to Mevastatin, or pages that link to Mevastatin or to this page or whose text contains "Mevastatin".

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Parent topics

• Hydroxymethylglutaryl-coenzyme A reductase inhibitor [r]: HMG-CoA reductase inhibitors which reduce 3-hydroxy-3-methyl-glutaryl CoA and lower cholesterol synthesis. ^[e]
• Hypercholesterolemia [r]: Presence of an abnormally large amount of cholesterol in the cells and plasma of the circulating blood. ^[e]
• Cholesterol [r]: Principal sterol of all higher animals. ^[e]

Statins

Type I statins

• Mevalonate [r]: A key chemical precursor in the biosynthesis of cholesterol. ^[e]
• Lovastatin [r]: Type I statin and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor used to treat hypercholesterolemia. ^[e]
• Pravastatin [r]: Type I Statin used to treat hypercholesterolemia. ^[e]
• Simvastatin [r]: A semisynthetic lipid-lowering drug derived from a compound produced by a mold of the genus Aspergillus and administered orally to lower a high cholesterol level in the blood by inhibiting the action of an enzyme catalyzing the synthesis of cholesterol. ^[e]

Type II statins

• Fluvastatin [r]: Fluorophenyl-based statin, HMG-CoA reductase inhibitor, for reduction of cholesterol, triglycerides and apo B. ^[e]
• Cerivastatin [r]: A type II statin formerly used to treat high cholesterol levels (hypercholesterolemia). ^[e]
• Atorvastatin [r]: Sold as Lipitor®, a type II statin used to treat high cholesterol (hypercholesterolemia), ^[e]
• Rosuvastatin [r]: A type II statin, marketed as Crestor®, used to treat high cholesterol levels. ^[e]