Filtration

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This article is about Conventional Filtration, for crossflow filtration see Crossflow filtration.

Filtration is a process by which solid components of a liquid-solid mixture are separated from the mixture by passing the mixture through a porous medium. In conventional filtration (as opposed to crossflow filtration) the incoming mixture, or feed, flows perpendicular to the porous medium. A layer of solids continues to build with time over the surface of the medium, while the flux of the feed through the medium approaches a zero asymptote. In bioprocessing, filtration is an early processing step during the recovery phase. It may be employed, for example, to retrieve a target product in solution from an undesired solid mass of freshly ruptured cells. Filtration is of particular value because it allows for an effect means of volume reduction, a crucial tool in early processing.

The Process

${\frac {1}{A}}{\frac {dV}{dt}}={\frac {\Delta p}{\mu _{o}R}}$

$R=R_{M}+R_{C}$

$R_{C}=\alpha \rho _{c}\left({\frac {V}{A}}\right)$

Failed to parse (SVG (MathML can be enabled via browser plugin): Invalid response ("Math extension cannot connect to Restbase.") from server "https://wikimedia.org/api/rest_v1/":): {\displaystyle \frac{1}{A}\frac{dV}{dt} =\frac{\Delta p}{μ_o\left ( \alpha\rho_c\left ( \frac{V}{A} \right ) + R_M \right )}}

Failed to parse (syntax error): {\displaystyle \frac{t}{\frac{V}{A}} = \frac{μ_oαρ_c}{2Δp}\left ( \frac{V}{A} \right ) + \frac{μ_oR_M}{Δp}}

History

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Invention and early development

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Recent developments

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Design and Operation

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Applications

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Examples

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