Connective tissue disease: Difference between revisions
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imported>Robert Badgett (New page: In medicine and rheumatology, '''connective tissue diseases''' are "a heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or fun...) |
imported>Robert Badgett |
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* [[Mixed connective tissue disease]] | * [[Mixed connective tissue disease]] | ||
* [[Polymyalgia rheumatica]] | * [[Polymyalgia rheumatica]] | ||
* [[Rheumatoid arthritis]] | * [[Rheumatoid arthritis]] - 80% a positive [[rheumatoid factor]] ([[autoantibody|autoantibodies]] against [[gamma-chain immunoglobulin]]s) | ||
** [[Sjogren's Syndrome]] | ** [[Sjogren's Syndrome]] - 60% have [[autoantibody|autoantibodies]] to [[SS-A antigen]] (Anti-Ro antigen) or [[SS-B antigen]] (Anti-La antigen)<ref name="pmid11014971">{{cite journal| author=Mavragani CP, Tzioufas AG, Moutsopoulos HM| title=Sjögren's syndrome: autoantibodies to cellular antigens. Clinical and molecular aspects. | journal=Int Arch Allergy Immunol | year= 2000 | volume= 123 | issue= 1 | pages= 46-57 | pmid=11014971 | ||
* [[Scleroderma]] | | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&retmode=ref&cmd=prlinks&id=11014971 }} </ref> | ||
* [[Scleroderma]] - most have [[Antinuclear antibody|antinuclear antibodies]] or [[autoantibody|autoantibodies]] to [[centromere]] or [[DNA topoisomerase I]] (Anti-Scl-70) | |||
Cartilage disease | Cartilage disease | ||
* [[Relapsing Polychondritis]] | |||
Collagen disease | Collagen disease | ||
* [[Alport Syndrome]] | |||
* [[Ehlers-Danlos Syndrome]] | |||
* [[Osteogenesis Imperfecta]] | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 19:04, 24 March 2010
In medicine and rheumatology, connective tissue diseases are "a heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides."[1]
Classification
- Dermatomyositis
- Systemic lupus erythematosus
- Mixed connective tissue disease
- Polymyalgia rheumatica
- Rheumatoid arthritis - 80% a positive rheumatoid factor (autoantibodies against gamma-chain immunoglobulins)
- Sjogren's Syndrome - 60% have autoantibodies to SS-A antigen (Anti-Ro antigen) or SS-B antigen (Anti-La antigen)[2]
- Scleroderma - most have antinuclear antibodies or autoantibodies to centromere or DNA topoisomerase I (Anti-Scl-70)
Cartilage disease
Collagen disease
References
- ↑ Anonymous (2024), Connective tissue disease (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Mavragani CP, Tzioufas AG, Moutsopoulos HM (2000). "Sjögren's syndrome: autoantibodies to cellular antigens. Clinical and molecular aspects.". Int Arch Allergy Immunol 123 (1): 46-57. PMID 11014971.