Nanobiotechnology: Difference between revisions
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NanoBiotechnology <ref> Nanofabrication and biosystems: integrating materials science, engineering, and biology | NanoBiotechnology <ref> Nanofabrication and biosystems: integrating materials science, engineering, and biology | ||
Harvey C. Hoch, Lynn Jelinski, Harold G. Craighead, Cambridge University Press, 1996</ref> | Harvey C. Hoch, Lynn Jelinski, Harold G. Craighead, Cambridge University Press, 1996</ref> | ||
<ref>Nanobiotechnology. Vol I and II. C.M.Neimeyer and C.A.Mirkin. (2007) Wiley-VCH. </ref><ref>NanoBioTechnology: bioinspired devices and materials of the future. O.Shoseyov, I. Levy. (2007) Humana Press.</ref> is an interdisciplinary field involving [[Nanotechnology]] and [[Biotechnology]]. It involves the use of nanostructured materials and devices for biological applications; and the use of biomolecules as nanoparticles or as components of nanodevices. Examples of current and potential applications of nanobiotechnology are: [[nanodots]] for imaging, [[nanobiosensors]], DNA based [[nanowires]], [[bionanoarrays]], [[nanomotors]], nanoscale imaging, [[nanorobots]], etc. | <ref>Nanobiotechnology. Vol I and II. C. M. Neimeyer and C. A. Mirkin. (2007) Wiley-VCH. </ref><ref>NanoBioTechnology: bioinspired devices and materials of the future. O. Shoseyov, I. Levy. (2007) Humana Press.</ref> is an interdisciplinary field involving [[Nanotechnology]] and [[Biotechnology]]. It involves the use of nanostructured materials and devices for biological applications; and the use of biomolecules as nanoparticles or as components of nanodevices. Examples of current and potential applications of nanobiotechnology are: [[nanodots]] for imaging, [[nanobiosensors]], DNA based [[nanowires]], [[bionanoarrays]], [[nanomotors]], nanoscale imaging, [[nanorobots]], etc. | ||
Perhaps the first application of nanotechnology in the biological context was the cocaine biosensor. The cocaine biosensor consisted of cocaine antibodies attached to a nanosized piezoelectric crystal. The binding of cocaine resulted in a change in the resonance frequency of the piezoelectric crystal. The small size of the crystal ensured that binding events would result in significant and measurable change in the resonance frequency. | Perhaps the first application of nanotechnology in the biological context was the cocaine biosensor. The cocaine biosensor consisted of cocaine antibodies attached to a nanosized piezoelectric crystal. The binding of cocaine resulted in a change in the resonance frequency of the piezoelectric crystal. The small size of the crystal ensured that binding events would result in significant and measurable change in the resonance frequency. | ||
The equipment used to produce nanoscaled objects is extremely sophisticated and costly. On the other hand, there are many nanoscale devices found in abundance in nature - this observation has motivated many (including Eric Drexler) to design objects using the principles of self assembly that are used by nature and to use biomacromolecules and bio-assemblies as building blocks. This later approach is known as the bottom up approach as opposed to the classic or top down approach for manufacturing which has evolved from semiconductor and microprocessor manufacturing technologies. Although conceptually elegant, practical demonstration of nanostructured self assembly is an experimental and theoretical challenge. Early successes in application of the self assembly principle were reported in the production of self-assembled monolayers (SAM) by the G.M.Whitesides group (now at Harvard). | The equipment used to produce nanoscaled objects is extremely sophisticated and costly. On the other hand, there are many nanoscale devices found in abundance in nature - this observation has motivated many (including Eric Drexler) to design objects using the principles of self assembly that are used by nature and to use biomacromolecules and bio-assemblies as building blocks. This later approach is known as the bottom up approach as opposed to the classic or top down approach for manufacturing which has evolved from semiconductor and microprocessor manufacturing technologies. Although conceptually elegant, practical demonstration of nanostructured self assembly is an experimental and theoretical challenge. Early successes in application of the self assembly principle were reported in the production of self-assembled monolayers (SAM) by the G. M. Whitesides group (now at Harvard). | ||
==External links== | |||
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http://www.nano.gov/nni_nanobiotechnology_rpt.pdf | http://www.nano.gov/nni_nanobiotechnology_rpt.pdf | ||
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http://www.rowland.harvard.edu/rjf/fischer/index.php | http://www.rowland.harvard.edu/rjf/fischer/index.php | ||
==References== | |||
{{reflist}} | |||
Revision as of 21:11, 20 February 2010
NanoBiotechnology [1] [2][3] is an interdisciplinary field involving Nanotechnology and Biotechnology. It involves the use of nanostructured materials and devices for biological applications; and the use of biomolecules as nanoparticles or as components of nanodevices. Examples of current and potential applications of nanobiotechnology are: nanodots for imaging, nanobiosensors, DNA based nanowires, bionanoarrays, nanomotors, nanoscale imaging, nanorobots, etc.
Perhaps the first application of nanotechnology in the biological context was the cocaine biosensor. The cocaine biosensor consisted of cocaine antibodies attached to a nanosized piezoelectric crystal. The binding of cocaine resulted in a change in the resonance frequency of the piezoelectric crystal. The small size of the crystal ensured that binding events would result in significant and measurable change in the resonance frequency.
The equipment used to produce nanoscaled objects is extremely sophisticated and costly. On the other hand, there are many nanoscale devices found in abundance in nature - this observation has motivated many (including Eric Drexler) to design objects using the principles of self assembly that are used by nature and to use biomacromolecules and bio-assemblies as building blocks. This later approach is known as the bottom up approach as opposed to the classic or top down approach for manufacturing which has evolved from semiconductor and microprocessor manufacturing technologies. Although conceptually elegant, practical demonstration of nanostructured self assembly is an experimental and theoretical challenge. Early successes in application of the self assembly principle were reported in the production of self-assembled monolayers (SAM) by the G. M. Whitesides group (now at Harvard).
External links
http://www.nano.gov/nni_nanobiotechnology_rpt.pdf
http://golgi.harvard.edu/branton/
http://ceesdekkerlab.tudelft.nl/research/projects/nanopores/
http://cancerres.aacrjournals.org/cgi/content/full/64/2/639
http://csb.mgh.harvard.edu/weissleder/research_projects
https://netfiles.uiuc.edu/gtimp/www/
http://www.rowland.harvard.edu/rjf/fischer/index.php
References
- ↑ Nanofabrication and biosystems: integrating materials science, engineering, and biology Harvey C. Hoch, Lynn Jelinski, Harold G. Craighead, Cambridge University Press, 1996
- ↑ Nanobiotechnology. Vol I and II. C. M. Neimeyer and C. A. Mirkin. (2007) Wiley-VCH.
- ↑ NanoBioTechnology: bioinspired devices and materials of the future. O. Shoseyov, I. Levy. (2007) Humana Press.