Microscopic polyangiitis: Difference between revisions
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'''Microscopic polyangiitis''' is a [[vasculitis]].<ref name="pmid16876669">{{cite journal| author=Bosch X, Guilabert A, Font J| title=Antineutrophil cytoplasmic antibodies. | journal=Lancet | year= 2006 | volume= 368 | issue= 9533 | pages= 404-18 | pmid=16876669 | '''Microscopic polyangiitis''' is a [[vasculitis]].<ref name="pmid16876669">{{cite journal| author=Bosch X, Guilabert A, Font J| title=Antineutrophil cytoplasmic antibodies. | journal=Lancet | year= 2006 | volume= 368 | issue= 9533 | pages= 404-18 | pmid=16876669 | ||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=16876669 | doi=10.1016/S0140-6736(06)69114-9 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> It preferentially attacks the kidneys and the lungs. | | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=16876669 | doi=10.1016/S0140-6736(06)69114-9 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> It preferentially attacks the kidneys and the lungs. | ||
Latest revision as of 12:36, 1 August 2010
Microscopic polyangiitis is a vasculitis.[1] It preferentially attacks the kidneys and the lungs.
Manifestations
Common manifestations are:
- About 90% of patients have glomerulonephritis similar to Wegener's granulomatosis[1]
- About half may have pulmonary hemorrhage[1]
- About half may have peripheral neuropathy.[2]
Diagnosis
Laboratory
Anti-neutrophil cytoplasmic antibodies (ANCA) are usually elevated. Characteristically, there are no immunoglobulin deposits.
References
- ↑ 1.0 1.1 1.2 Bosch X, Guilabert A, Font J (2006). "Antineutrophil cytoplasmic antibodies.". Lancet 368 (9533): 404-18. DOI:10.1016/S0140-6736(06)69114-9. PMID 16876669. Research Blogging.
- ↑ Cattaneo L, Chierici E, Pavone L, Grasselli C, Manganelli P, Buzio C et al. (2007). "Peripheral neuropathy in Wegener's granulomatosis, Churg-Strauss syndrome and microscopic polyangiitis.". J Neurol Neurosurg Psychiatry 78 (10): 1119-23. DOI:10.1136/jnnp.2006.111013. PMID 17299018. Research Blogging.