Proteinuria: Difference between revisions
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In [[medicine]], '''proteinuria''' is "the presence of proteins in the urine, an indicator of kidney diseases."<ref>{{MeSH}}</ref> | In [[medicine]], '''proteinuria''' is "the presence of proteins in the urine, an indicator of kidney diseases."<ref>{{MeSH}}</ref> Proteinuria may occur in [[acute kidney injury]] or [[chronic kidney disease]]. | ||
==Diagnosis== | ==Diagnosis== | ||
Revision as of 08:49, 4 January 2011
In medicine, proteinuria is "the presence of proteins in the urine, an indicator of kidney diseases."[1] Proteinuria may occur in acute kidney injury or chronic kidney disease.
Diagnosis
The standard dipstick test only measures albumin.
The sulfosalicylic acid (SSA) test measure all protein.
Spot protein/creatinine ratio
One study found that in the presence of stable renal function, a protein/creatinine ratio:[2]
- > 3.5 (mg/mg) suggests nephrotic syndrome
- < 0.2 is within normal limits
Spot urine albumin/creatinine ratio
In adults, albuminuria is a more sensitive than total protein in detecting chronic kidney disease from many glomerular diseases.[3]
- <30 mg/g is a normal albumin-creatinine ratio
- 30-300 mg/g is microalbuminuria
References
- ↑ Anonymous (2024), Proteinuria (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Ginsberg JM, Chang BS, Matarese RA, Garella S (1983). "Use of single voided urine samples to estimate quantitative proteinuria.". N Engl J Med 309 (25): 1543-6. PMID 6656849.
- ↑ National Kidney Foundation (2002). "K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.". Am J Kidney Dis 39 (2 Suppl 1): S1-266. PMID 11904577.