Transfusion reaction: Difference between revisions
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This is a minor, acute reaction suggested by negative a [[Coombs' test]], no free hemoglobin in the plasma, and no hemoglobin in the urine. | This is a minor, acute reaction suggested by negative a [[Coombs' test]], no free hemoglobin in the plasma, and no hemoglobin in the urine. | ||
===ABO incompatibility reaction=== | ===Hemolytic reactions=== | ||
====ABO incompatibility reaction==== | |||
ICD9: {{ICD9|999.6}} | ICD9: {{ICD9|999.6}} | ||
This reaction usually causes acute hemolysis. | This reaction usually causes acute hemolysis. | ||
===Rh incompatibility reaction=== | ====Rh incompatibility reaction==== | ||
ICD9: {{ICD9|999.7}} | ICD9: {{ICD9|999.7}} | ||
This reaction usually causes delayed hemolysis. | This reaction usually causes delayed hemolysis. | ||
===Transfusion related acute lung injury (TRALI)=== | ====Transfusion related acute lung injury (TRALI)==== | ||
ICD9: {{ICD9|518.7}} | ICD9: {{ICD9|518.7}} | ||
This is an acute reaction. | This is an acute reaction. | ||
Revision as of 19:02, 6 November 2008
A classification has been proposed by the American Association of Blood Banks (AABB).[1] In addition, the classification below is based on ICD9.
Immunologic
Febrile, nonhemolytic transfusion reaction (FNHTR)
This is a minor, acute reaction suggested by negative a Coombs' test, no free hemoglobin in the plasma, and no hemoglobin in the urine.
Hemolytic reactions
ABO incompatibility reaction
ICD9: 999.6
This reaction usually causes acute hemolysis.
Rh incompatibility reaction
ICD9: 999.7
This reaction usually causes delayed hemolysis.
ICD9: 518.7
This is an acute reaction.
Nonimmunologic
Chemical reactions
- Hemosiderosis
- Hypocalcemia from citrate toxicity
- Hyperkalemia
- Metabolic alkalosis and hypokalemia due to citrate
Transmission of infection
Other reactions
- Hypothermia
- Circulatory overload
- Hypotension associated with leukoreduced blood
- Transfusion-related acute lung injury (pulmonary leukoagglutinin reaction) (TRALI)
References
- ↑ Sanders RP, Geiger TL, Heddle N, Pui CH, Howard SC (April 2007). "A revised classification scheme for acute transfusion reactions". Transfusion 47 (4): 621–8. DOI:10.1111/j.1537-2995.2007.01163.x. PMID 17381620. Research Blogging.