Bradykinin receptor: Difference between revisions
imported>Robert Badgett (New page: {{subpages}} '''Bradykinin receptors''' are "cell surface receptors that bind bradykinin and related kinins with high affinity and trigger intracellular changes which influence the...) |
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Bradykinin receptors are G-Protein-coupled [[cell surface receptor]]s. | Bradykinin receptors are G-Protein-coupled [[cell surface receptor]]s. | ||
==Classification== | |||
===Bradykinin B1 receptor=== | |||
"A subtype of bradykinin receptor that is induced in response to inflammation. It may play a role in chronic inflammation and has a high specificity for kinins lacking the C-terminal arginine such as des-Arg(10)-kallidin and des-Arg(9)-bradykinin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."<ref>{{MeSH|Bradykinin B1 receptor}}</ref> | |||
===Bradykinin B2 receptor=== | |||
"A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of [[bradykinin]] and kallidin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."<ref>{{MeSH|Bradykinin B2 receptor}}</ref> | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 22:54, 15 June 2008
Bradykinin receptors are "cell surface receptors that bind bradykinin and related kinins with high affinity and trigger intracellular changes which influence the behavior of cells. The identified receptor types (B-1 and B-2, or BK-1 and BK-2) recognize endogenous kallidin; t-kinins; and certain bradykinin fragments as well as bradykinin itself."[1]
Bradykinin receptors are G-Protein-coupled cell surface receptors.
Classification
Bradykinin B1 receptor
"A subtype of bradykinin receptor that is induced in response to inflammation. It may play a role in chronic inflammation and has a high specificity for kinins lacking the C-terminal arginine such as des-Arg(10)-kallidin and des-Arg(9)-bradykinin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."[2]
Bradykinin B2 receptor
"A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of bradykinin and kallidin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."[3]
References
- ↑ Anonymous (2024), Bradykinin receptor (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Anonymous (2024), Bradykinin B1 receptor (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Anonymous (2024), Bradykinin B2 receptor (English). Medical Subject Headings. U.S. National Library of Medicine.