Absolute risk reduction: Difference between revisions

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In clinical [[epidemiology]] and [[evidence-based medicine]], the [[absolute risk reduction]] is a measure that compares the frequency of a clinical outcome in group of patients exposed to a factor compared to a control group of patients.<ref name="pmid15313996">{{cite journal |author=Barratt A, Wyer PC, Hatala R, ''et al'' |title=Tips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat |journal=CMAJ |volume=171 |issue=4 |pages=353–8 |year=2004 |pmid=15313996 |doi=10.1503/cmaj.1021197 |url=http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=15313996}}</ref> This measure should be contrasted with the [[relative risk reduction]].
In clinical [[epidemiology]] and [[evidence-based medicine]], the [[absolute risk reduction]] is a measure that compares the frequency of a clinical outcome in group of patients exposed to a factor compared to a control group of patients.<ref name="pmid15313996">{{cite journal |author=Barratt A, Wyer PC, Hatala R, ''et al'' |title=Tips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat |journal=CMAJ |volume=171 |issue=4 |pages=353–8 |year=2004 |pmid=15313996 |doi=10.1503/cmaj.1021197 |url=http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=15313996}}</ref> This measure should be contrasted with the [[relative risk reduction]].
Most journal articles fail to report absolute measures which may lead to exaggerated perceptions of results.<ref>Welch HG et al.Ratio measures in leading medical journals: structured review of accessibility of underlying absolute risks.BMJ. 2006 Dec 16;333(7581):1248. Epub 2006 Oct 23. PMID 17060338</ref>


==Calculations==
==Calculations==

Revision as of 07:58, 15 May 2008

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In clinical epidemiology and evidence-based medicine, the absolute risk reduction is a measure that compares the frequency of a clinical outcome in group of patients exposed to a factor compared to a control group of patients.[1] This measure should be contrasted with the relative risk reduction.

Most journal articles fail to report absolute measures which may lead to exaggerated perceptions of results.[2]

Calculations

Two-by-two table for a randomized-controlled trial or cohort study
Outcome
Present Absent
Experimental group Cell A Cell B Total in the experimental group
Control group Cell C Cell D Total in the control group
Total with the outcome Total without the outcome

References

  1. Barratt A, Wyer PC, Hatala R, et al (2004). "Tips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat". CMAJ 171 (4): 353–8. DOI:10.1503/cmaj.1021197. PMID 15313996. Research Blogging.
  2. Welch HG et al.Ratio measures in leading medical journals: structured review of accessibility of underlying absolute risks.BMJ. 2006 Dec 16;333(7581):1248. Epub 2006 Oct 23. PMID 17060338

See also