Rosuvastatin: Difference between revisions

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imported>David E. Volk
(New page: {{subpages}} [[Image:Rosuvastatin structure.jpg|right|thumb|200px|{{#ifexist:Template:Rosuvastatin structure.jpg/credit|{{Rosuvastatin structure.jpg/credit}}<br/>|}}Rosuvastatin, a class I...)
 
imported>David E. Volk
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[[Image:Rosuvastatin structure.jpg|right|thumb|200px|{{#ifexist:Template:Rosuvastatin structure.jpg/credit|{{Rosuvastatin structure.jpg/credit}}<br/>|}}Rosuvastatin, a class II statin.]]  
[[Image:Rosuvastatin structure.jpg|right|thumb|350px|{{#ifexist:Template:Rosuvastatin structure.jpg/credit|{{Rosuvastatin structure.jpg/credit}}<br/>|}}Rosuvastatin, a class II statin.]]  


'''Rosuvastatin''', marketed as '''Crestor''',  is a class II statin used to treat high cholesterol levels ([[hypercholesterolemia]]), prevent [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish the formation of [[atherosclerosis|arterial plaque]].  It is a [[Hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-CoA reductase inhibitor]] that decreases the conversion of HMG-CoA to  [[mevalonate]], a key chemical precursor of [[cholesterol]].   
'''Rosuvastatin''', marketed as '''Crestor''',  is a class II statin used to treat high cholesterol levels ([[hypercholesterolemia]]), prevent [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish the formation of [[atherosclerosis|arterial plaque]].  It is a [[Hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-CoA reductase inhibitor]] that decreases the conversion of HMG-CoA to  [[mevalonate]], a key chemical precursor of [[cholesterol]].   


Its official chemical IUPAC name is (E,3R,5R)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C<sub>22</sub>H<sub>28</sub>FN<sub>3</sub>O<sub>6</sub>S.
Its official chemical IUPAC name is (E,3R,5R)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C<sub>22</sub>H<sub>28</sub>FN<sub>3</sub>O<sub>6</sub>S.

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Rosuvastatin, a class II statin.

Rosuvastatin, marketed as Crestor, is a class II statin used to treat high cholesterol levels (hypercholesterolemia), prevent heart attacks and strokes, and to diminish the formation of arterial plaque. It is a HMG-CoA reductase inhibitor that decreases the conversion of HMG-CoA to mevalonate, a key chemical precursor of cholesterol.

Its official chemical IUPAC name is (E,3R,5R)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C22H28FN3O6S.