Eplerenone: Difference between revisions
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[[Image:Eplerenone.jpg|right|thumb|350px|{{#ifexist:Template:Eplerenone.jpg/credit|{{Eplerenone.jpg/credit}}<br/>|}}'''Eplerenone''', an aldosterone receptor agonist.]] | [[Image:Eplerenone.jpg|right|thumb|350px|{{#ifexist:Template:Eplerenone.jpg/credit|{{Eplerenone.jpg/credit}}<br/>|}}'''Eplerenone''', an aldosterone receptor agonist.]] | ||
'''Eplerenone''' is an [[aldosterone receptor]] agonist, similar to [[spironolactone]]. Because it inhibits the negative regulatory feedback of [[aldosterone]] on [[renin]] secretion, increased plasma renin, and serum aldosterone, occur with its use. Eplerenone selectively binds to [[mineralocorticoid receptors]] relative to its binding to [[glucocorticoid]], [[progesterone]] and [[androgen]] receptors. | '''Eplerenone''' is an [[aldosterone receptor]] agonist, similar to [[spironolactone]]. Because it inhibits the negative regulatory feedback of [[aldosterone]] on [[renin]] secretion, increased plasma renin, and serum aldosterone, occur with its use. Eplerenone selectively binds to [[mineralocorticoid receptors]] relative to its binding to [[glucocorticoid]], [[progesterone]] and [[androgen]] receptors. | ||
Revision as of 20:49, 6 April 2009
Eplerenone is an aldosterone receptor agonist, similar to spironolactone. Because it inhibits the negative regulatory feedback of aldosterone on renin secretion, increased plasma renin, and serum aldosterone, occur with its use. Eplerenone selectively binds to mineralocorticoid receptors relative to its binding to glucocorticoid, progesterone and androgen receptors.
External links
- Eplerenone - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Template:MedMaster
- Template:DrugBank