Aldosterone: Difference between revisions
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Revision as of 09:11, 6 February 2009
Aldosterone, also called (11ß)-11,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-al, is a steroid hormone. It is the major mineralcorticoid and it therefore controls electrolyte levels, blood pressure and hydration. Aldosterone is synthesized from corticosterone by oxidation of the C-18 methyl group to form an aldehyde.
Primary aldosteronism underlies about 10% of cases of resistant hypertension.[1]
References
- ↑ Douma S, Petidis K, Doumas M, et al (June 2008). "Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study". Lancet 371 (9628): 1921–6. DOI:10.1016/S0140-6736(08)60834-X. PMID 18539224. Research Blogging.