Cysteine: Difference between revisions
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[[Image:Cysteine Biosynthesis DEVolk.png|right|thumb|350px|{{#ifexist:Template:Cysteine Biosynthesis DEVolk.png/credit|{{Cysteine Biosynthesis DEVolk.png/credit}}<br/>|}}Biosynthesis of cysteine, catalyzed by cystathionine synthase and cystathionase.]] | |||
'''Cysteine''' is one of the twenty common [[amino acid|amino acids]]. It is one of two amino acids which contain a sulfur atom, the other being [[methionine]], and is one of the two amino acids which contain a hydroxyl group, the other being [[threonine]]. Cysteine is a precursor of methionine in the activated methyl cycle, and it is synthesized from a condensation reaction between the amino acid serine and homocysteine. | '''Cysteine''' is one of the twenty common [[amino acid|amino acids]]. It is one of two amino acids which contain a sulfur atom, the other being [[methionine]], and is one of the two amino acids which contain a hydroxyl group, the other being [[threonine]]. Cysteine is a precursor of methionine in the activated methyl cycle, and it is synthesized from a condensation reaction between the amino acid serine and homocysteine. | ||
==Biosynthesis== | ==Biosynthesis== | ||
The enzyme [[cystathionine synthase]] catalyzes the condensation reaction of serine with homocysteine which produces cystathione and water. Another enzyme, [[cystathionase]], then catalyzes the deamination and cleavage of cystathione to produce cysteine and [[alpha-ketobutyrate|<math>\alpha</math>-ketobutyrate]]. In this cleavage reaction, serine acts as the carbon skeleton and homocysteine provides the sulfur atom. | The enzyme [[cystathionine synthase]] catalyzes the condensation reaction of serine with homocysteine which produces cystathione and water. Another enzyme, [[cystathionase]], then catalyzes the deamination and cleavage of cystathione to produce cysteine and [[alpha-ketobutyrate|<math>\alpha</math>-ketobutyrate]]. In this cleavage reaction, serine acts as the carbon skeleton and homocysteine provides the sulfur atom. | ||
Revision as of 17:57, 19 December 2007
Cysteine is one of the twenty common amino acids. It is one of two amino acids which contain a sulfur atom, the other being methionine, and is one of the two amino acids which contain a hydroxyl group, the other being threonine. Cysteine is a precursor of methionine in the activated methyl cycle, and it is synthesized from a condensation reaction between the amino acid serine and homocysteine.
Biosynthesis
The enzyme cystathionine synthase catalyzes the condensation reaction of serine with homocysteine which produces cystathione and water. Another enzyme, cystathionase, then catalyzes the deamination and cleavage of cystathione to produce cysteine and -ketobutyrate. In this cleavage reaction, serine acts as the carbon skeleton and homocysteine provides the sulfur atom.
