CURB-65: Difference between revisions

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* blood pressure less than 90 systolic or diastolic [[blood pressure]] 60 or less
* blood pressure less than 90 systolic or diastolic [[blood pressure]] 60 or less
* age 65 or older
* age 65 or older
A variation is the CURB-age.<ref name="pmid19691619">{{cite journal| author=Myint PK, Sankaran P, Musonda P, Subramanian DN, Ruffell H, Smith AC et al.| title=Performance of CURB-65 and CURB-age in community-acquired pneumonia. | journal=Int J Clin Pract | year= 2009 | volume= 63 | issue= 9 | pages= 1345-50 | pmid=19691619
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=19691619 | doi=10.1111/j.1742-1241.2009.02147.x }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>


==Predicting death from pneumonia==
==Predicting death from pneumonia==

Revision as of 20:40, 23 November 2009

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CURB-65 is a validated score for predicting mortality in community-acquired pneumonia[1] and infection of any site[2]. The CURB-65 is based on the earlier CURB score[3] and is recommended by the British Thoracic Society for the assessment of severity of pneumonia.[4]

The score is an acronym for each of the risk factors measured. Each risk factor scores one point, for a maximum score of 5:

  • confusion (defined as an AMT of 8 or less)
  • urea greater than 7 mmol/l (19.6 mg/dl)
  • respiratory rate of 30 breaths per minute or greater
  • blood pressure less than 90 systolic or diastolic blood pressure 60 or less
  • age 65 or older

A variation is the CURB-age.[5]

Predicting death from pneumonia

The risk of death increases as the score increases:

  • 0—0.7%
  • 1—3.2%
  • 2—13.0%
  • 3—17.0%
  • 4—41.5%
  • 5—57.0%

The CURB-65 has been compared to the pneumonia severity index in predicting mortality from pneumonia.[6]

Predicting death from any infection

A cohort study of patients with any type of infection (half of the patients had pneumonia), the risk of death increases as the score increases[2]:

  • 0 to 1 <5% mortality
  • 2 to 3 < 10% mortality
  • 4 to 5 15-30% mortality

References

  1. Lim WS, van der Eerden MM, Laing R, et al (2003). "Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study". Thorax 58 (5): 377-82. PMID 12728155[e]
  2. 2.0 2.1 Howell MD, Donnino MW, Talmor D, Clardy P, Ngo L, Shapiro NI (2007). "Performance of severity of illness scoring systems in emergency department patients with infection". Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 14 (8): 709-14. DOI:10.1197/j.aem.2007.02.036. PMID 17576773. Research Blogging.
  3. Lim WS, Macfarlane JT, Boswell TC, et al (2001). "Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines". Thorax 56 (4): 296-301. PMID 11254821[e]
  4. (2001) "BTS Guidelines for the Management of Community Acquired Pneumonia in Adults". Thorax 56 Suppl 4: IV1-64. PMID 11713364[e]
  5. Myint PK, Sankaran P, Musonda P, Subramanian DN, Ruffell H, Smith AC et al. (2009). "Performance of CURB-65 and CURB-age in community-acquired pneumonia.". Int J Clin Pract 63 (9): 1345-50. DOI:10.1111/j.1742-1241.2009.02147.x. PMID 19691619. Research Blogging.
  6. Aujesky D, Auble TE, Yealy DM, et al (2005). "Prospective comparison of three validated prediction rules for prognosis in community-acquired pneumonia". Am. J. Med. 118 (4): 384-92. DOI:10.1016/j.amjmed.2005.01.006. PMID 15808136. Research Blogging.

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