Head and neck cancer: Difference between revisions
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'''Head and neck cancer''' includes "Soft tissue tumors or cancer arising from the mucosal surfaces of the [[lip]]; oral cavity; [[pharynx]]; [[larynx]]; and cervical [[esophagus]]. Other sites included are the [[nose]] and [[paranasal sinuses]]; [[salivary glands]]; [[thyroid gland]] and [[parathyroid glands]] and [[melanoma]]and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)<ref>{{<MeSH>}}</ref> | '''Head and neck cancer''' includes "Soft tissue tumors or cancer arising from the mucosal surfaces of the [[lip]]; oral cavity; [[pharynx]]; [[larynx]]; and cervical [[esophagus]]. Other sites included are the [[nose]] and [[paranasal sinuses]]; [[salivary glands]]; [[thyroid gland]] and [[parathyroid glands]] and [[melanoma]] and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)<ref>{{<MeSH>}}</ref> | ||
==Cause / etiology== | ==Cause / etiology== | ||
===By location=== | ===By location=== | ||
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{{PDQ-treatment|http://www.cancer.gov/cancertopics/pdq/treatment/salivarygland/HealthProfessional/page5|Salivary Gland Cancer}} | {{PDQ-treatment|http://www.cancer.gov/cancertopics/pdq/treatment/salivarygland/HealthProfessional/page5|Salivary Gland Cancer}} | ||
===By location=== | ===By location=== | ||
====Thyroid==== | |||
Radioactive [[iodine]] concentrates in the thyroid. | |||
===By histologic type==== | ===By histologic type==== | ||
====Carcinoma==== | ====Carcinoma==== | ||
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| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&retmode=ref&cmd=prlinks&id=18784101 | doi=10.1056/NEJMoa0802656 }} </ref> | | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&retmode=ref&cmd=prlinks&id=18784101 | doi=10.1056/NEJMoa0802656 }} </ref> | ||
[[Radiotherapy]] is the first-line palliative treatment for [[feline squamous cell carcinoma]], with adjuvant therapy with [[NSAID]]s such as [[piroxicam]] and [[meloxicam]], as well as experimental protocols using adjuvant [[hyperthermia]] and [[hyperbaric oxygen]]. [[Bleomycin]] and [[carboplatin]] are | [[Radiotherapy]] is the first-line palliative treatment for [[feline squamous cell carcinoma]], with adjuvant therapy with [[NSAID]]s such as [[piroxicam]] and [[meloxicam]], as well as experimental protocols using adjuvant [[hyperthermia]], [[phototherapy]] and [[hyperbaric oxygen]]. [[Bleomycin]] and [[carboplatin]] are core drugs for palliative chemotherapy. | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 12:41, 31 May 2010
Head and neck cancer includes "Soft tissue tumors or cancer arising from the mucosal surfaces of the lip; oral cavity; pharynx; larynx; and cervical esophagus. Other sites included are the nose and paranasal sinuses; salivary glands; thyroid gland and parathyroid glands and melanoma and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)[1]
Cause / etiology
By location
Oropharynx
Human papillomavirus (HPV) is a risk factor for oropharyngeal cancer.[2]
Lip
Pipe and cigar smoking are risk factors.
By histological type
Treatment
Head and Neck Cancer treatment information from the National Cancer Institute's Physician Data Query
Salivary Gland Cancer treatment information from the National Cancer Institute's Physician Data Query
By location
Thyroid
Radioactive iodine concentrates in the thyroid.
By histologic type=
Carcinoma
Cetuximab chimeric recombinant monoclonal antibody that blocks epidermal growth factor receptor (EGFR).[2]In the major randomized controlled trial, the percentage of cells that are EGFR positive did not seen to predict the response to cetuximab.[3]
Radiotherapy is the first-line palliative treatment for feline squamous cell carcinoma, with adjuvant therapy with NSAIDs such as piroxicam and meloxicam, as well as experimental protocols using adjuvant hyperthermia, phototherapy and hyperbaric oxygen. Bleomycin and carboplatin are core drugs for palliative chemotherapy.
References
- ↑ {{<MeSH>}}
- ↑ 2.0 2.1 Haddad RI, Shin DM (2008). "Recent advances in head and neck cancer.". N Engl J Med 359 (11): 1143-54. DOI:10.1056/NEJMra0707975. PMID 18784104. Research Blogging.
- ↑ Vermorken JB, Mesia R, Rivera F, Remenar E, Kawecki A, Rottey S et al. (2008). "Platinum-based chemotherapy plus cetuximab in head and neck cancer.". N Engl J Med 359 (11): 1116-27. DOI:10.1056/NEJMoa0802656. PMID 18784101. Research Blogging.