Fatty liver: Difference between revisions
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imported>Robert Badgett (New page: In medicine, '''fatty liver''', also called '''hepatic steatosis''' or '''liver steatosis''' is "lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver...) |
imported>Robert Badgett No edit summary |
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Fatty liver includes [[steatohepatitis]]. | Fatty liver includes [[steatohepatitis]]. | ||
==Etiology / cause== | |||
Fatty liver and [[steatohepatitis]] may be caused by the [[single-nucleotide polymorphism]]s [http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=2854116 rs2854116] (c.455T>C) and [http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=2854117 rs2854117] (c.482C>T) of [[apolipoprotein C-III]] which are also associated with [[insulin resistance]] and [[hypertriglyceridemia]].<ref name="pmid20335584">{{cite journal| author=Petersen KF, Dufour S, Hariri A, Nelson-Williams C, Foo JN, Zhang XM et al.| title=Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease. | journal=N Engl J Med | year= 2010 | volume= 362 | issue= 12 | pages= 1082-9 | pmid=20335584 | |||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&retmode=ref&cmd=prlinks&id=20335584 | doi=10.1056/NEJMoa0907295 }} </ref> | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 10:08, 30 March 2010
In medicine, fatty liver, also called hepatic steatosis or liver steatosis is "lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of triglycerides, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of fatty acids."[1]
Fatty liver includes steatohepatitis.
Etiology / cause
Fatty liver and steatohepatitis may be caused by the single-nucleotide polymorphisms rs2854116 (c.455T>C) and rs2854117 (c.482C>T) of apolipoprotein C-III which are also associated with insulin resistance and hypertriglyceridemia.[2]
References
- ↑ Anonymous (2024), Fatty liver (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Petersen KF, Dufour S, Hariri A, Nelson-Williams C, Foo JN, Zhang XM et al. (2010). "Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease.". N Engl J Med 362 (12): 1082-9. DOI:10.1056/NEJMoa0907295. PMID 20335584. Research Blogging.