Natriuretic peptide: Difference between revisions
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In [[physiology]], '''natriuretic peptides''' are "Peptides that regulate the water-electrolyte balance in the body, also known as natriuretic peptide hormones. Several have been sequenced ([[atrial natriuretic factor]]; [[brain natriuretic peptide]]; [[c-type natriuretic peptide]])."<ref>{{MeSH}}</ref> In addition, N-terminal pro-B-type natriuretic peptide (NT-proBNP) is an inactive peptide that is co-secreted with [[brain natriuretic peptide]].<ref name="pmid19815122">{{cite journal| author=Steinhart B, Thorpe KE, Bayoumi AM, Moe G, Januzzi JL, Mazer CD| title=Improving the diagnosis of acute heart failure using a validated prediction model. | journal=J Am Coll Cardiol | year= 2009 | volume= 54 | issue= 16 | pages= 1515-21 | pmid=19815122 | In [[physiology]], '''natriuretic peptides''' are "Peptides that regulate the water-electrolyte balance in the body, also known as natriuretic peptide hormones. Several have been sequenced ([[atrial natriuretic factor]]; [[brain natriuretic peptide]]; [[c-type natriuretic peptide]])."<ref>{{MeSH}}</ref> In addition, N-terminal pro-B-type natriuretic peptide (NT-proBNP) is an inactive peptide that is co-secreted with [[brain natriuretic peptide]].<ref name="pmid19815122">{{cite journal| author=Steinhart B, Thorpe KE, Bayoumi AM, Moe G, Januzzi JL, Mazer CD| title=Improving the diagnosis of acute heart failure using a validated prediction model. | journal=J Am Coll Cardiol | year= 2009 | volume= 54 | issue= 16 | pages= 1515-21 | pmid=19815122 | ||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=19815122 | doi=10.1016/j.jacc.2009.05.065 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> | | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=19815122 | doi=10.1016/j.jacc.2009.05.065 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> | ||
Revision as of 05:42, 23 August 2010
In physiology, natriuretic peptides are "Peptides that regulate the water-electrolyte balance in the body, also known as natriuretic peptide hormones. Several have been sequenced (atrial natriuretic factor; brain natriuretic peptide; c-type natriuretic peptide)."[1] In addition, N-terminal pro-B-type natriuretic peptide (NT-proBNP) is an inactive peptide that is co-secreted with brain natriuretic peptide.[2]
Brain natriuretic peptide and N-terminal pro-B-type natriuretic peptide are used as diagnostic tests to detect heart failure.[3][4] Both have a sensitivity over 90% but have a specificity of less than 70%.[3][4]
References
- ↑ Anonymous (2024), Natriuretic peptide (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Steinhart B, Thorpe KE, Bayoumi AM, Moe G, Januzzi JL, Mazer CD (2009). "Improving the diagnosis of acute heart failure using a validated prediction model.". J Am Coll Cardiol 54 (16): 1515-21. DOI:10.1016/j.jacc.2009.05.065. PMID 19815122. Research Blogging.
- ↑ 3.0 3.1 Mant J, Doust J, Roalfe A, Barton P, Cowie MR, Glasziou P et al. (2009). "Systematic review and individual patient data meta-analysis of diagnosis of heart failure, with modelling of implications of different diagnostic strategies in primary care.". Health Technol Assess 13 (32): 1-207, iii. DOI:10.3310/hta13320. PMID 19586584. Research Blogging.
- ↑ 4.0 4.1 Balion C, Santaguida PL, Hill S, Worster A, McQueen M, Oremus M et al. (2006). "Testing for BNP and NT-proBNP in the diagnosis and prognosis of heart failure.". Evid Rep Technol Assess (Full Rep) (142): 1-147. PMID 17764210.