Japanese encephalitis virus: Difference between revisions
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*[[Spastic paralysis]] | *[[Spastic paralysis]] | ||
*[[Flaccid paralysis]] (occurs in rare instances) | *[[Flaccid paralysis]] (occurs in rare instances) | ||
As the infection progresses without treatment it may reach an acute level | As the infection progresses without treatment it may reach an acute level. When such a high level of infection occurs, there are serious side affects which include moderate brain damage ,varying degrees of paralysis,<ref>http://www.dhpe.org/infect/jpenceph.html</ref> as well as seizures and death.<ref>http://www.wrongdiagnosis.com/j/japanese_encephalitis/symptoms.htm</ref> | ||
==Transmission and Epidemiology== | ==Transmission and Epidemiology== | ||
Japanese encephalitis virus is considered an [[arthropod]] virus called an arbovirus. The vector that spreads this arbovirus is a mosquito.<ref>http://www.answers.com/topic/japanese-encephalitis</ref>The Culicine mosquito from the genus Culex are responsible for many diseases such as [[Dengue fever]], [[Yellow fever]], [[Venezuelan equine encephalitis]], as well as the Japanese encephalitis. Their eggs are laid in still water that is either clean water or contaminated with organic waste. These eggs are also resistant to [[dessication]] for several months.<ref>http://www.cbwinfo.com/Biological/Vectors/Culicine.html</ref> | Japanese encephalitis virus is considered an [[arthropod]] virus called an arbovirus. The vector that spreads this arbovirus is a mosquito.<ref>http://www.answers.com/topic/japanese-encephalitis</ref>The Culicine mosquito from the genus Culex are responsible for many diseases such as [[Dengue fever]], [[Yellow fever]], [[Venezuelan equine encephalitis]], as well as the Japanese encephalitis. Their eggs are laid in still water that is either clean water or contaminated with organic waste. These eggs are also resistant to [[dessication]] for several months.<ref>http://www.cbwinfo.com/Biological/Vectors/Culicine.html</ref> | ||
The first reported suspicion of JE was within the last century and first documented in horses as well as humans in Japan, which explains the origin of it's name. The virus was first isolated from human brain tissue in rabbits in 1924. The specific species of Culex mosquitos linked to the JE virus is the Culex (Cx) tritaeniorhynchus<ref>http://www.vadscorner.com/jelsk.html</ref> | The first reported suspicion of JE was within the last century and first documented in horses as well as humans in Japan, which explains the origin of it's name. The virus was first isolated from human brain tissue in rabbits in 1924. The specific species of Culex mosquitos linked to the JE virus is the Culex (Cx) tritaeniorhynchus<ref>http://www.vadscorner.com/jelsk.html</ref> | ||
Infection into a healthy human begins with an infected mosquito. This mosquito lands on a human's skin and bites the victim, this transmits the virus into the bloodstream and is able to cause viraemia, the virus being spread intially from the bite site which allows it access to the rest of the body through the circulatory system.<ref>http://en.wikipedia.org/wiki/Arbovirus</ref> | |||
==Ecology== | ==Ecology== | ||
Revision as of 22:35, 21 April 2009
| Japanese Encephalitis Virus (JE) | ||||||
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| Scientific classification | ||||||
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General information and Symptoms
Originally named Japanese B encephalitis virus in order to aid in distinguishing this species of encephalitis with an agent causing Von Economo's type A encephalitis species, it has since been modified to a more simple name without the B.[1] Japanese encephalitis (JE) is a virus that infects the central nervous system, which consists of the brain and spinal cord. It may range from mild to acute infection. Mild Symptoms include flu-like illness that may include:[2]
A severe infection symptoms may include mild symptoms as well as:[3]
- Rapid onset
- Stupor
- Disorientation
- Coma
- Tremors
- Occasional convlusions (occurs more often in infants)
- Spastic paralysis
- Flaccid paralysis (occurs in rare instances)
As the infection progresses without treatment it may reach an acute level. When such a high level of infection occurs, there are serious side affects which include moderate brain damage ,varying degrees of paralysis,[4] as well as seizures and death.[5]
Transmission and Epidemiology
Japanese encephalitis virus is considered an arthropod virus called an arbovirus. The vector that spreads this arbovirus is a mosquito.[6]The Culicine mosquito from the genus Culex are responsible for many diseases such as Dengue fever, Yellow fever, Venezuelan equine encephalitis, as well as the Japanese encephalitis. Their eggs are laid in still water that is either clean water or contaminated with organic waste. These eggs are also resistant to dessication for several months.[7] The first reported suspicion of JE was within the last century and first documented in horses as well as humans in Japan, which explains the origin of it's name. The virus was first isolated from human brain tissue in rabbits in 1924. The specific species of Culex mosquitos linked to the JE virus is the Culex (Cx) tritaeniorhynchus[8]
Infection into a healthy human begins with an infected mosquito. This mosquito lands on a human's skin and bites the victim, this transmits the virus into the bloodstream and is able to cause viraemia, the virus being spread intially from the bite site which allows it access to the rest of the body through the circulatory system.[9]
Ecology
Structure and Metabolism
Pathology
Japanese Encephalitis is antigenically linked to several other flaviviruses and belongs to the family Flaviviridae.[10] An Antigen is a substance that causes that causes the body to illicit an immune response such as the production of antibody through the introduction of a foreign substance such as a virus or bacteria into the body.[11]
Current Research
References
- ↑ http://www.vadscorner.com/jelsk.html
- ↑ http://www.cdc.gov/ncidod/dvbid/jencephalitis/qa.htm
- ↑ http://www.wrongdiagnosis.com/j/japanese_encephalitis/symptoms.htm
- ↑ http://www.dhpe.org/infect/jpenceph.html
- ↑ http://www.wrongdiagnosis.com/j/japanese_encephalitis/symptoms.htm
- ↑ http://www.answers.com/topic/japanese-encephalitis
- ↑ http://www.cbwinfo.com/Biological/Vectors/Culicine.html
- ↑ http://www.vadscorner.com/jelsk.html
- ↑ http://en.wikipedia.org/wiki/Arbovirus
- ↑ http://www.vadscorner.com/jelsk.html
- ↑ http://www.thefreedictionary.com/antigenic