Klebsiella pneumoniae: Difference between revisions

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==Genome structure==
==Genome structure==
There are lots of research being done on sequencing the genome.  Some places such as ([[Genome Sequencing Center]])at Washington University in St. Louis and ([[PLOS genetics]]).  At Genome Sequencing Center the genome was named Klebsiella pneumoniae subsp. pneumoniae MGH 78578 ATCC 700721 [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genome&Cmd=ShowDetailView&TermToSearch=21205]  It was isolated from 66 year old male patient in 1994.  It contained one chromosome of 5.3Mbp.  There are plasmids pKPN3, pKPN4, pKPN5, pKPN6 and pKPN7 the plasmid length afre respectively 0.18, 0.11, 0.089, 0.0043, and 0.0035 Mbp.  Similarly, at PLOS genetics Kp342 was studied.  It contained one chromose of 5,641,239 bp.  There are two plasmids pKP187 of length 182,922 bp. and pKP91 of length 91,096 bp [http://www.ttaxus.com/files/fouts2008-klebsiella.pdf].  The whole genome is sequenced.  At both places the DNA was circular.
There are lots of research being done on sequencing the genome.  Some places such as ([[Genome Sequencing Center]])at Washington University in St. Louis and ([[PLOS genetics]]).  At Genome Sequencing Center the genome was named Klebsiella pneumoniae subsp. pneumoniae MGH 78578 ATCC 700721 [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genome&Cmd=ShowDetailView&TermToSearch=21205]  It was isolated from 66 year old male patient in 1994.  It contained one chromosome of 5.3Mbp.  There are plasmids pKPN3, pKPN4, pKPN5, pKPN6 and pKPN7 the plasmid length afre respectively 0.18, 0.11, 0.089, 0.0043, and 0.0035 Mbp.  Similarly, at PLOS genetics Kp342 was studied.  It contained one chromose of 5,641,239 bp.  There are two plasmids pKP187 of length 182,922 bp. and pKP91 of length 91,096 bp (5)[http://www.ttaxus.com/files/fouts2008-klebsiella.pdf].  The whole genome is sequenced.  At both places the DNA was circular.


==Cell structure and metabolism==
==Cell structure and metabolism==

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Classification

Klebsiella pnemoniae
Klebsiella pneumoniae.jpg
Scientific classification
Kingdom: Eubacteria
Phylum: Proteobacteria
Class: Gamma Proteobacteria
Order: Pseudomonadales
Family: Pseudomonadaceae
Genus: Pseudomonas
Species: putida
Binomial name
Pseudomonas putida

Klebsiella pnemoniae is a species of Genus: Klebsiella. The Family: Enterobacteriaceae. The Order: Enterobacteriales. The Class: Gammaproteobacteria. The Phylum: Proteobacteria. and The Domain: Bacteria.

Image of Klebsiella pnemoniae

Klebsiella pneumoniae.jpg Image is from Microbiologia! [1]

Description and significance

K. pneumoniae is a gram negative bacteria. It is faculative aerobic, meaning it is has characteristic features of becoming aerobic and anaerobic. It is rod shaped and its dimensions are 2 X 0.5 micro meter. K. pneumoniae is also known as nasty bacteria. Klebsiella (pneumoniae) is commonly found in bacteria directed pneumoniae patients. Friedlancer C. Uber was the first person to discover that Klebsiella is a pathogenic bacteria that causes pneumoniae (2). The 160nm thick fine fiber capsule makes the bacteria pathogenic (3)[2]. This bacteria is found in different places in human body such as gastrointestinal tract and nasopharynx. (4) Naturally it is found in the soil, water, vegetables and sewage.

Genome structure

There are lots of research being done on sequencing the genome. Some places such as (Genome Sequencing Center)at Washington University in St. Louis and (PLOS genetics). At Genome Sequencing Center the genome was named Klebsiella pneumoniae subsp. pneumoniae MGH 78578 ATCC 700721 [3] It was isolated from 66 year old male patient in 1994. It contained one chromosome of 5.3Mbp. There are plasmids pKPN3, pKPN4, pKPN5, pKPN6 and pKPN7 the plasmid length afre respectively 0.18, 0.11, 0.089, 0.0043, and 0.0035 Mbp. Similarly, at PLOS genetics Kp342 was studied. It contained one chromose of 5,641,239 bp. There are two plasmids pKP187 of length 182,922 bp. and pKP91 of length 91,096 bp (5)[4]. The whole genome is sequenced. At both places the DNA was circular.

Cell structure and metabolism

Ecology

Pathology

References

(1)

(2)Friedlander C. Uber die scizomyceten bei der acuten fibrosen pneumonie. Arch Pathol Anat Physiol Klin Med 1882. 87:319-24

(3)Amako, K., Meno, Y., and Takade, A. "Fine Structures of the Capsules of Klebsiella pneumoniae and Escherichia coli K1". Journal of Bacteriology. 1988. Volume 170, No. 10. p. 4960-4962[5]

(4)Casewell M, Talsania H G. Predominance of certain klebsiella capsular types in hospitals in the United Kingdom. J Infect. 1979;1:77–79.